Coefficient Factor for Graft Weight Estimation from Preoperative Computed Tomography Volumetry in Living Donor Liver Transplantation

Coefficient Factor for Graft Weight Estimation from Preoperative Computed Tomography Volumetry in Living Donor Liver Transplantation
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DOI:
10.1002/lt.22239
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发表时间:
2011-04-01
影响因子:
4.6
通讯作者:
Inomata, Yukihiro
Inomata, Yukihiro
中科院分区:
医学2区
文献类型:
--
作者:
Yoneyama, Tetsuji;Asonuma, Katsuhiro;Inomata, Yukihiro

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在活体肝移植(LDLT)的临床环境中,通常会发现术前计算机断层扫描体积测定法估计的移植物体积与后台测量的实际移植物重量(AGW)之间存在差异。在这项研究中,我们试图找到相关的系数因子,估计移植物体积的AGW。对25例LDLT受者(17例肝硬化和8例形态正常的家族性淀粉样多发性神经病)的全肝进行了评价,以比较肝硬化和非肝硬化的正常肝脏。此外,还评价了LDLT中使用的右叶移植物(n = 39)和左叶移植物(n = 35),以进一步确定估计的移植物体积与AGW之间的相关性。估计的肝脏体积和实际的肝脏重量之间的相关系数为1.01,而在全肝淀粉样多发性神经病,而它是0.85。在部分肝移植中,右叶移植为0.84,左叶移植为0.85。总之,我们建议,相关系数为0.85,应适用于准确计算移植物重量的体积估计术前计算机断层扫描在LDLT。肝移植17:369-372,2011。(C)2011年AASLD。
In the clinical setting of living donor liver transplantation (LDLT), it is common to find a discrepancy between the graft volume estimated by preoperative computed tomography volumetry and the actual graft weight (AGW) measured on the back-table. In this study, we attempt to find the coefficient factor that correlates the estimated graft volume to the AGW. Whole livers explanted in 25 LDLT recipients (17 cirrhotic and 8 morphologically normal with familial amyloid polyneuropathy) were evaluated to compare cirrhotic livers and noncirrhotic normal livers. In addition, right lobe grafts (n = 39) and left lobe grafts (n = 35) used in LDLTs were also evaluated to further determine the correlation between estimated graft volume and AGW. The correlation coefficient between estimated liver volume and actual liver weight was 1.01 in whole cirrhotic livers, whereas it was 0.85 in whole livers with familial amyloid polyneuropathy. In the partial liver grafts, it was 0.84 in right lobe grafts and 0.85 in left lobe grafts. In conclusion, we suggest that a correlation coefficient of 0.85 should be applied for the accurate calculation of the graft weight from the volume estimated by preoperative computed tomography in LDLT. Liver Transpl 17:369-372, 2011. (C) 2011 AASLD.