Cobalt-catalyzed cross-coupling reactions
Cobalt-catalyzed cross-coupling reactions
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DOI：
10.1039/b805142a
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发表时间：
2008-01-01
影响因子：
4.9
通讯作者：
Moncomble, Aurelien
中科院分区：
文献类型：
--
作者：
Gosmini, Corinne;Begouin, Jeanne-Marie;Moncomble, Aurelien
在过去的几年中，我们和其他小组已经证明，经济的钴盐可以有利地取代昂贵和有毒的催化剂用于交叉偶联反应。这些钴催化的反应大大扩展了官能化化合物的范围。在这些偶联反应中可以容许各种敏感的官能团，并且可以涉及各种有机化合物RX（R =烷基、炔基、芳基、烯丙基和X =卤化物：F、Cl、Br、I和甚至三氟甲磺酸酯）。在这里，我们描述了我们在这一领域的贡献，从有机金属物种或通过直接交叉偶联制备广泛的官能化化合物。
In the last few years, we and other groups have demonstrated that economical cobalt salts can advantageously replace expensive and toxic catalysts for cross coupling reactions. These cobalt-catalyzed reactions have considerably extended the range of functionalized compounds. A variety of sensitive functional groups can be tolerated in these coupling reactions and various organic compounds RX could be involved (R = alkyl, alkynyl, aryl, allyl and X = halides: F, Cl, Br, I and even triflates). Here, we describe our contributions in this area for the preparation of a broad range of functionalized compounds from organometallic species or by direct cross-coupling.