HIV infection and patterns of risk among women drug injectors and crack users in low and high sero-prevalence sites
HIV infection and patterns of risk among women drug injectors and crack users in low and high sero-prevalence sites
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低血清流行率和高血清流行率地区女性注射吸毒者和快克吸毒者的艾滋病毒感染和风险模式
作者：
S. Tortu;M. Beardsley;Sherry Deren;M. Williams;H. Mccoy;M. Stark;A. Estrada;Marjorie F. Goldstein
随着美国女性艾滋病病例的持续增加，需要更好地了解女性的行为风险模式，以便为干预工作提供信息。数据来自2945名女性吸毒者和吸毒者。统计分析比较了社会人口统计变量、终身行为风险模式、艾滋病毒血清流行率和性传播疾病病史，并分别在16个血清流行率较低和4个血清流行率较高的地点确定了艾滋病毒感染的预测因素。根据风险模式，构建了四个行为定义的亚组，并比较了艾滋病毒血清流行率。在低和高血清流行点之间的比较中，在所检查的大多数变量上，以及在预测艾滋病毒的社会人口学特征和风险模式的相对重要性方面，存在显著差异。注射毒品和性交换都是感染的独立、显著的行为预测因素，每个预测因素的优势比之间没有显著差异。HIV血清流行率在四个亚组之间有显著差异。干预措施必须量身定制，以解决在低和高血清流行率地点观察到的妇女之间的差异。注射、吸毒和交换性行为在美国女性感染艾滋病毒的传播中扮演着重要角色。针对妇女的预防工作应解决行为风险模式的差异。需要对进行性行为交换的妇女进行积极和创新的干预。艾滋病研究必须调查社会经济因素如何影响妇女感染艾滋病毒的风险。
As AIDS cases among US women continue to increase, a better understanding of women's behavioural risk patterns is needed to inform intervention efforts. Data were from 2,945 women drug injectors and crack users. Statistical analyses compared sociodemographic variables, lifetime behavioural risk patterns, HIV sero-prevalence and history of sexually transmitted diseases, and determined predictors of HIV infection separately in 16 low and four high sero-prevalence sites. Based on risk patterns, four behaviourally-defined sub-groups were constructed, and rates of HIV sero-prevalence were compared. In comparisons between low and high sero-prevalence sites, there were significant differences on most variables examined, and in the relative importance of the sociodemographic characteristics and risk patterns predicting HIV. Drug injection and sex exchange were each independent, significant, behavioural predictors of infection, with no significant difference between the odds ratios attributed to each predictor. HIV sero-prevalence was significantly different among four sub-groups. Interventions must be tailored to address observed differences among women in low and high sero-prevalence sites. Injection drug use and exchanging sex each play a major role in the transmission of HIV infection to US women. Prevention efforts targeted at women should address differences in behavioural risk patterns. Aggressive and innovative interventions are needed for women who exchange sex. AIDS research must investigate how socioeconomic factors impact women's risk for HIV infection.
纽约和迈阿密女性吸毒者艾滋病毒感染的预测因素。
影响因子：
1.6
作者：
Tortu,S;McCoy,HV;Beardsley,M;Deren,S;McCoy,CB
通讯作者：
McCoy,CB
预防艾滋病毒和性病感染。
影响因子：
5.1
作者：
Chesney,MA
通讯作者：
Chesney,MA