ORIGIN OF GENETIC CODE
ORIGIN OF GENETIC CODE
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DOI：
10.1016/0022-2836(68)90392-6
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发表时间：
1968-01-01
影响因子：
5.6
通讯作者：
CRICK, FHC
中科院分区：
文献类型：
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作者：
CRICK, FHC
描述了遗传密码的一般特征。据认为，最初只有少数氨基酸被编码，但大多数可能的密码子很快就被投入使用。在随后的步骤中，当额外的氨基酸能够赋予选择性优势时，它们被取代，直到最终代码以其目前的形式被冻结。
The general features of the genetic code are described. It is considered that originally only a few amino acids were coded, but that most of the possible codons were fairly soon brought into use. In subsequent steps additional amino acids were substituted when they were able to confer a selective advantage, until eventually the code became frozen in its present form.