What are the actual incidence and mortality rates of intracerebral hemorrhage?
What are the actual incidence and mortality rates of intracerebral hemorrhage?
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DOI：
10.1007/s10143-002-0222-0
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发表时间：
2002-08-01
影响因子：
2.8
通讯作者：
Inagawa, T
中科院分区：
文献类型：
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作者：
Inagawa, T
从1991年到1996年，我们在日本出云市通过计算机断层扫描或磁共振成像（证实为脑出血）诊断出267例原发性脑出血（ICH）患者。所有年龄段的粗发病率为52/10万/年；然而，为了估计实际的发病率和死亡率，我们应该考虑那些未经证实推定死于脑出血的人。从1991年到1996年，我们审查了出云市（人口84,854人）的所有3,903份死亡证明，并结合已证实的和可能的脑出血计算了脑出血的发病率和死亡率。我们在死亡证明上诊断出34例患者可能患有脑出血，当这些患者与267例已证实患有脑出血的患者相加时，所有年龄段的粗发病率和经年龄和性别调整的发病率分别为每年59/100,000和每年53/100,000。其中，19%（57例）在第3天（第0天定义为出血之日）死亡，1个月和2年的总生存率分别为77%和65%。所有年龄段的粗死亡率和年龄和性别调整后的30天死亡率分别为每年14/10万和12/10万。当包括那些可能死于脑出血的患者时，脑出血的实际发病率远高于迄今为止的报道，实际生存率仍然令人不满意。
From 1991 through 1996, we diagnosed 267 patients in Izumo City, Japan, as having primary intracerebral hemorrhage (ICH) by computed tomography or magnetic resonance imaging (proven ICH). The crude incidence rate was 52/100,000 per year for all ages; however, to estimate the actual incidence and mortality rates, we should take into account those who were presumed without confirmation to have died of ICH. From 1991 through 1996, we reviewed all 3,903 death certificates for the city of Izumo (population 84,854) and calculated the incidence and mortality rates of ICH by combining proven and possible ICH. We diagnosed 34 patients as having possible ICH on their death certificates and, when these were added to the 267 with proven ICH, the crude and the age- and sex-adjusted incidence rates for all ages became 59/100,000 per year and 53/100,000 per year, respectively. Of these, 19% (57) died by day 3 (day 0 being defined as the day of hemorrhage), and the overall survival rates at I month and 2 years were 77% and 65%, respectively. The crude and the age- and sex-adjusted 30-day mortality rates for all ages became 14/100,000 per year and 12/100,000 per year, respectively. When including those patients who may have died of ICH, the actual incidence rate of ICH is much higher than that reported to date, and the actual survival rate is still unsatisfactory.