Multiple spectroscopic analyses reveal the fate and metabolism of sulfamide herbicide triafamone in agricultural environments
Multiple spectroscopic analyses reveal the fate and metabolism of sulfamide herbicide triafamone in agricultural environments
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多重光谱分析揭示了磺酰胺除草剂三氟草酮在农业环境中的归宿和代谢
DOI：
10.1016/j.envpol.2017.06.046
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发表时间：
2017
影响因子：
8.9
通讯作者：
Zhu Guonian
中科院分区：
文献类型：
--
作者：
Wang Mengcen;Qian Yuan;Liu Xiaoyu;Wei Peng;Deng Man;Wang Lei;Wu Huiming;Zhu Guonian
磺酰胺类除草剂Triafamone在亚洲水稻田已被广泛应用。但其在环境中的命运和转化尚未确立。通过水稻模拟试验结合多种光谱分析，分离鉴定了三种新的粉虫酮代谢产物，包括羟基粉虫酮（HTA）、羟基粉虫酮糖苷（HTAG）和恶唑烷二酮粉虫酮（OTA）。当以34.2克活性成分/公顷的浓度向稻田施用triafamone时，主要分布在稻田土壤和水中，然后根据一级速率模型迅速消散，半衰期为4.3-11.0天。作为主要的转化途径，triafamone被水稻植株同化并解毒为HTAG，而其余的被还原为HTA并随后形成OTA。糙米在衰老阶段已摄入0.0016 mg/kg的粉虫酮，但危害商<1，表明长期食用含粉虫酮的糙米相对安全。本研究的结果表明，triafamone是积极代谢在农业环境中，并阐明环境暴露于这些三嗪或恶唑烷二酮部分，含有代谢物和它们的潜在影响之间的联系是必要的。
Triafamone, a sulfamide herbicide, has been extensively utilized for weed control in rice paddies in Asia. However, its fate and transformation in the environment have not been established. Through a rice paddy microcosm-based simulation trial combined with multiple spectroscopic analyses, we isolated and identified three novel metabolites of triafamone, including hydroxyl triafamone (HTA), hydroxyl triafamone glycoside (HTAG), and oxazolidinedione triafamone (OTA). When triafamone was applied to rice paddies at a concentration of 34.2 g active ingredient/ha, this was predominantly distributed in the paddy soil and water, and then rapidly dissipated in accordance with the first-order rate model, with half-lives of 4.3–11.0 days. As the main transformation pathway, triafamone was assimilated by the rice plants and was detoxified into HTAG, whereas the rest was reduced into HTA with subsequent formation of OTA. At the senescence stage, brown rice had incurred triafamone at a concentration of 0.0016 mg/kg, but the hazard quotient was <1, suggesting that long-term consumption of the triafamone-containing brown rice is relatively safe. The findings of the present study indicate that triafamone is actively metabolized in the agricultural environment, and elucidation of the link between environmental exposure to these triazine or oxazolidinedione moieties that contain metabolites and their potential impacts is warranted.