Left Ventricular Sphericity Index is a reproducible bedside echocardiographic measure of geometric change between acute phase Takotsubo's syndrome and acute anterior myocardial infarction
Left Ventricular Sphericity Index is a reproducible bedside echocardiographic measure of geometric change between acute phase Takotsubo's syndrome and acute anterior myocardial infarction
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DOI：
10.1016/j.ijcha.2020.100547
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发表时间：
2020-08-01
影响因子：
2.9
通讯作者：
Tan, Timothy C.
中科院分区：
文献类型：
--
作者：
Khanna, Shaun;Bhat, Aditya;Tan, Timothy C.
背景：左室球形指数（LVSI）是一种简单、快速、可重复性好的评价左室几何形态改变的指标。我们研究的目的是评估LVSI作为两种疾病过程中的快速鉴别工具的效用; Takotsubo综合征（TS）和前壁心肌梗死（AMI），在没有显著的左心室收缩功能障碍的情况下。方法：对我院收治的急性期TS患者（2013年1月至2018年12月）进行评价（n=66）。进行了全面二维经胸超声心动图检查的患者被纳入主要分析（n=50），并与急性前壁AMI患者队列（n=50）年龄匹配。对患者的人口统计学、临床和超声心动图参数进行评估。双平面LVSI计算为平均短轴和长轴长度在4-和2-腔心尖views.Results：共50 TS患者（64.3 +/- 13.7岁，18%的男性）与50 AMI（62.10 +/- 12.84岁，74%的男性）患者相匹配。除糖尿病外，基线心血管风险因素无显著差异（AMI 34% vs TS 17%，p = 0.034）。两组之间的LV质量（p=0.10）或LVEF（p=0.52）也无差异。有趣的是，TS（0.60 ± 0.06）与AMI（0.52 ± 0.07）之间的平均LVSI存在显著差异（p
Background: Left ventricular sphericity index (LVSI) is a simple, quick and reproducible measure to evaluate LV geometric changes. The aim of our study was to evaluate the utility of LVSI as a rapid discrimination tool in two disease processes; Takotsubo's Syndrome (TS) and Anterior Myocardial Infarction (AMI), in the absence of significant left ventricular systolic dysfunction.Methods: Consecutive patients with acute phase TS admitted to our institution (Jan 2013 - Dec 2018) were evaluated (n=66). Patients with a comprehensive two-dimensional transthoracic echocardiogram were included in primary analysis (n=50) and age-matched with a cohort of patients with acute anterior AMI (n=50). Appraisal of demographic, clinical and echocardiographic parameters of patients was undertaken. Biplane LVSI was calculated as an average of the short- and long-axis length in the 4- and 2-chamber apical views.Results: A total of 50 TS patients (64.3 +/- 13.7 years, 18% men) were matched with 50 AMI (62.10 +/- 12.84 years, 74% men) patients. There was no significant difference in baseline cardiovascular risk factors other than diabetes mellitus (AMI 34% vs TS 17%, p = 0.034). There was also no difference in LV mass (p=0.10) or LVEF (p=0.52) between the two groups. Interestingly, there was a significant difference in mean LVSI between TS (0.60 +/- 0.06) vs AMI (0.52 +/- 0.07) (p