Influence of diabetes mellitus on patients with lumbar spinal stenosis: A nationwide population-based study
Influence of diabetes mellitus on patients with lumbar spinal stenosis: A nationwide population-based study
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DOI：
10.1371/journal.pone.0213858
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发表时间：
2019-03-15
期刊：
影响因子：
3.7
通讯作者：
Kim, Insoo
中科院分区：
文献类型：
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作者：
Lee, Chang Kyu;Choi, Sun Kyu;Kim, Insoo
目的探讨腰椎管狭窄症（LSS）合并糖尿病（DM）患者合并症、医疗费用及手术疗效的关系。方法从2005 - 2007年韩国国民健康保险服务数据库中收集LSS患者资料（n = 14298）。随访8年后，根据结果测量比较“糖尿病组”（n = 3,478）和“非糖尿病组”（n = 10,820）。采用Cox比例风险回归来检验糖尿病、高血压（HTN）、心血管疾病（CVD）、慢性肾脏疾病（CKD）、脑血管疾病（CbVD）和LSS手术之间的关系。在DM和LSS患者中，还评估了接受腰椎手术的患者的入院率、医疗费用以及总体生存率。结果糖尿病组的死亡率是非糖尿病组的1.35倍。糖尿病合并HTN等合并症患者(风险比[HR]， 1.40； 95%可信区间[CI]， 1.25-1.56
PurposeTo evaluate the relationship between comorbidities, medical cost, and surgical outcome in patients with lumbar spinal stenosis (LSS) and diabetes mellitus (DM).MethodsData on patients with LSS (n = 14,298) were collected from the Korean National Health Insurance Service database from 2005 to 2007. After 8 years of follow-up, a "DM group" (n = 3,478) and a "non-DM group" (n = 10,820) were compared according to outcome measures. Cox proportional hazard regressions were performed to examine the relationship between DM, hypertension (HTN), cardiovascular disease (CVD), chronic kidney disease (CKD), cerebrovascular disease (CbVD), and surgery for LSS. The admission rate and medical cost as well asthe overall survival rate for those who underwent lumbar surgery were also assessed among patients with DM and LSS.ResultsMortality was about 1.35 times higher in the DM group than in the non-DM group. Patients with DM and comorbidities including HTN (hazard ratio [HR], 1.40; 95% confidence interval [CI], 1.25-1.56; p