Translational progress on tumor biomarkers.

Translational progress on tumor biomarkers.
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肿瘤生物标志物的转化进展。

DOI:
10.1111/1759-7714.12294
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发表时间:
2015-11
期刊:
影响因子:
2.9
通讯作者:
Zhang J
Zhang J
中科院分区:
医学3区
文献类型:
--
作者:
Guo H;Zhou X;Lu Y;Xie L;Chen Q;Keller ET;Liu Q;Zhou Q;Zhang J

文献摘要

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迫切需要将基础研究成果应用于临床。特别是,应由实验室研究人员根据临床需求开展机制研究,以提高癌症患者的生存率和生活质量。到目前为止,转化医学已经在癌症生物学中得到了解决,特别是在新的肿瘤生物标志物的鉴定和表征方面。本文就转化医学在肿瘤生物标志物研究中的最新进展及临床应用前景作一综述。
There is an urgent need to apply basic research achievements to the clinic. In particular, mechanistic studies should be developed by bench researchers, depending upon clinical demands, in order to improve the survival and quality of life of cancer patients. To date, translational medicine has been addressed in cancer biology, particularly in the identification and characterization of novel tumor biomarkers. This review focuses on the recent achievements and clinical application prospects in tumor biomarkers based on translational medicine.