Fibromyalgia syndrome: Overnight falls in arterial oxygen saturation
Fibromyalgia syndrome: Overnight falls in arterial oxygen saturation
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DOI：
10.1016/s0002-9343(96)00067-8
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发表时间：
1996-07-01
影响因子：
5.9
通讯作者：
Cabello, AM
中科院分区：
文献类型：
--
作者：
Lario, BA;Valdivielso, JLA;Cabello, AM
目的：纤维肌痛综合征（FS）的病理生理学已报道了提示缺氧的睡眠改变和肌肉变化。我们测试的假设，即FS患者显示福尔斯在动脉血氧饱和度的血红蛋白（SaO（2）%）在sleep.Patients和方法：隔夜SaO（2）%测量数字脉搏血氧饱和度在28个随机选择的妇女谁符合1990年美国流变学学会诊断标准的FS和15个类似的控制。考虑到脉搏血氧测定的结果，并为了评估睡眠呼吸暂停综合征（SAS）作为夜间去饱和度原因的可能存在，将埃普沃思嗜睡量表（ESS）邮寄给患者和对照组。ESS评分高于10分的患者和对照组进行多导睡眠图研究。FS患者夜间最低SaO（2）%较低（85.8 +/- 1.3对比对照组90.7 +/- 0.9，P < 0.05），去饱和次数更多（8.3 +/- 1.8对比对照组2.7 +/- 0.8，P < 0.05）和更多的去饱和度/小时（1.3 +/- 0.3对比对照组0.4 +/- 0.1，P < 0.05），夜间SaO（2）%
PURPOSE: Sleep alterations and muscular changes suggesting hypoxia have been reported in fibromyalgia syndrome (FS) pathophysiology. We tested the hypothesis that patients with FS show falls in the oxygen saturation of hemoglobin in arterial blood (SaO(2)%) during sleep.PATIENTS AND METHODS: Overnight SaO(2)% was measured by digital pulse oximetry in 28 randomly selected women who met 1990 American College of Rheumatology criteria for the diagnosis of FS and 15 similar controls. Considering the results of pulse oximetry and in order to evaluate the possible presence of a sleep apnea syndrome (SAS) as the reason for the nocturnal desaturations, the Epworth Sleepiness Scale (ESS) was mailed to the patients and controls. Patients and controls who had a score higher than 10 on the ESS underwent a polysomnographic study.RESULTS: Patients with FS showed lower overnight minimum SaO(2)% (85.8 +/- 1.3 versus 90.7 +/- 0.9 in controls, P < 0.05), greater number of desaturations (8.3 +/- 1.8 versus 2.7 +/- 0.8 in controls, P < 0.05) and more desaturations/hour (1.3 +/- 0.3 versus 0.4 +/- 0.1 in controls, P < 0.05), more night minutes in SaO(2)%