Cherenkov luminescence imaging of shallow sources in semitransparent media.
Cherenkov luminescence imaging of shallow sources in semitransparent media.
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半透明介质中浅源的切伦科夫发光成像。
DOI：
10.1117/1.jbo.24.2.026001
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发表时间：
2019
影响因子：
3.5
通讯作者：
Tai,Yuan-Chuan
中科院分区：
文献类型：
--
作者：
Komarov,Sergey;Liu,Yongjian;Tai,Yuan-Chuan
实验研究了具有不同β粒子能量的同位素Cu64、F18、Au198、P32和Br76在半透明生物等效介质中的切伦科夫发光成像（CLI）。这项工作的主要重点是描述当源在与β粒子范围相当的深度时的CLI。将实验结果与蒙特卡罗（MC）模拟结果进行比较，微调模拟参数，以更好地模拟幻体材料。该方法可用于估计不同幻体材料和同位素的CLI性能。这项工作还证明了高能β粒子的一些独特特性，这些特性可能对CLI有益，包括利用从物体中逸出的β粒子进行成像的可能性。
We experimentally investigated the Cherenkov luminescence imaging (CLI) of the isotopes with different beta particles energies (Cu64, F18, Au198, P32, and Br76) in semitransparent biological equivalent media. The main focus of this work is to characterize the CLI when the sources are at the depth comparable with the range of beta particles. The experimental results were compared with Monte Carlo (MC) simulation results to fine tune the simulation parameters to better model the phantom materials. This approach can be applied to estimate the CLI performance for different phantom materials and isotopes. This work also demonstrates some unique properties of high energy beta particles that can be beneficial for CLI, including the possibility to utilize the betas escaped from the object for imaging purposes.