The Utility of Economic Measures to Quantify the Burden of Tinnitus in Affected Individuals: A Scoping Review.

The Utility of Economic Measures to Quantify the Burden of Tinnitus in Affected Individuals: A Scoping Review.
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DOI:
10.1007/s41669-021-00273-8
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发表时间:
2022-01
期刊:
PharmacoEconomics - open
影响因子:
--
通讯作者:
Baguley DM
Baguley DM
中科院分区:
其他
文献类型:
--
作者:
Daoud E;Caimino C;Akeroyd MA;Noreña AJ;Baguley DM

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耳鸣是一种慢性主观疾病,影响患者的健康相关生活质量(HRQoL),需要多学科干预。在卫生经济学中,质量调整生命年(QALs)和支付意愿(WTP)是在成本效益、成本效用或成本效益分析中评价治疗效果的重要指标。在何种程度上,这些经济措施已被用于耳鸣的研究还没有调查。本次范围审查的目的是探索现有研究的结果和局限性,并提供如何使用这些经济措施来量化受影响个体的耳鸣负担的见解。根据系统性综述和荟萃分析首选报告项目(PRISMA)方法框架进行范围审查。搜索策略涉及四个电子数据库。记录包括当QF或WTP测量个人的主要或次要投诉是耳鸣。共确定了15项研究:3项WTP评估研究和12项QALY评估研究,使用直接基于偏好的措施(PBM)(n = 4),间接PBM(n = 7)和疾病特异性心理测量工具(n = 1)。迄今为止,PBM在评估耳鸣患者HRQoL方面的使用有限,这是一个重要的发现。需要使用可靠的经济方法进行进一步的研究,并关注患者对治疗的支付意愿或他们对当前健康状况的偏好。在耳鸣研究中应用PBM不仅对医疗决策过程至关重要,而且对改善以患者为中心的护理也至关重要。
Tinnitus is a chronic subjective condition that impacts patients’ health-related quality of life (HRQoL) and requires multidisciplinary interventions. In health economics, quality-adjusted life years (QALYs) and willingness to pay (WTP) are essential for evaluating treatment effectiveness in cost-effectiveness, cost-utility, or cost-benefit analysis. The extent to which these economic measures have been used in tinnitus research has not been investigated. The objectives of this scoping review were to explore findings and limitations of existing studies and provide an insight into how these economic measures could be used to quantify the burden of tinnitus in affected individuals. A scoping review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) methodological framework. The search strategy involved four electronic databases. Records were included when QALYs or WTP were measured in individuals whose primary or secondary complaint was tinnitus. A total of 15 studies were identified: three WTP assessment studies and 12 QALY assessment studies using direct preference-based measures (PBMs) (n = 4), indirect PBMs (n = 7), and a disease-specific psychometric instrument (n = 1). The limited use to date of PBMs to assess HRQoL in tinnitus patients is an important finding. Further studies using reliable economic methods and focusing on patients’ WTP for treatment or their preference for their current health state are needed. Applying PBMs in tinnitus research is crucial not only for the healthcare decision-making process but also to improve patient-centred care.
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