Seahorse TLR5 gene responses to Vibrio vulnificus infection, which in combination with scuticociliates causes heavy reductions in seahorse aquaculture.
Seahorse TLR5 gene responses to Vibrio vulnificus infection, which in combination with scuticociliates causes heavy reductions in seahorse aquaculture.
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DOI：
10.1111/jfd.12893
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发表时间：
2018-09
影响因子：
2.5
通讯作者：
G. Qin;Y. Zhang;Bo Zhang;Xin Wang;Jianping Yin;Q. Lin
中科院分区：
文献类型：
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作者：
G. Qin;Y. Zhang;Bo Zhang;Xin Wang;Jianping Yin;Q. Lin
海马因其独特的体型和雄性怀孕策略而在全球广受欢迎（Lin, Fan et al., 2016），在某些亚洲国家，海马也被视为最重要的中药（Chen, Wang, & Huang, 2015; Koldewey & Martin‐Smith, 2010）。然而，由于栖息地的破坏和大量的贸易，近几十年来野生海马的数量大大减少（Lourie, Pollom, & Foster, 2016）。海马养殖已成为解决高市场需求的重要和潜在的候选产品（Qin, Wang, Tan, & Lin, 2017）。然而，广泛传播的疾病被认为是海马养殖的重要瓶颈，也是近年来科研面临的严峻挑战（Declercq et al., 2014; Wang, Zhang, Qin, Luo, & Lin, 2016）。在过去的10年里，条纹海马（Hippocampus erectus）一直是中国最受欢迎的养殖物种（Lin et al., 2012）；然而，这些动物经常受到疾病事件的影响（Lin, Zhang, Liu, & Xiao, 2016; Qin et al., 2017; Wang et al., 2016）。我们于2012年首次区分出了龟头虫感染的海马。在5个以上的养殖场发现了类似的疾病，这些事件导致10万多只海马死亡，每个养殖场养殖的海马死亡率为20%-80%（图1a）。然而，在这些情况下，用于对抗scuticociliates的策略并不是特别有效。鱼类通常被两种或两种以上的病原体感染，而共同感染会导致某些传染病的严重程度（Xu, Shoemaker, & Lafrentz, 2014）。为
Seahorses are popular throughout the world because of their unique body shape and male pregnancy strategy (Lin, Fan et al., 2016), and they are also regarded as the most important traditional Chinese medicine (TCM) in certain Asian countries (Chen, Wang, & Huang, 2015; Koldewey & Martin‐Smith, 2010). However, due to habitat destruction and heavy trade, wild seahorse populations have greatly declined in recent decades (Lourie, Pollom, & Foster, 2016). Seahorse aquaculture has become an important and potential candidate for addressing the high market demand (Qin, Wang, Tan, & Lin, 2017). However, widespread diseases are considered an important bottleneck for seahorse culturing and represent a serious challenge for scientific research in recent years (Declercq et al., 2014; Wang, Zhang, Qin, Luo, & Lin, 2016).The lined seahorse (Hippocampus erectus) has been the most popular cultured species in China over the past 10 years (Lin et al., 2012); however, these animals have been impacted by frequent disease events (Lin, Zhang, Liu, & Xiao, 2016; Qin et al., 2017; Wang et al., 2016). We first distinguished scuticociliate‐infected seahorses in 2012. Similar diseases were found at more than five farms, and these events led to the death of more than 100,000 seahorses and 20%–80% mortality of the cultured seahorses each farm (Figure 1a). However, the strategies used against scuticociliates were not particularly effective in these cases. Fish are commonly infected by two or more pathogens, and co‐infections contribute to the severity of certain infectious diseases (Xu, Shoemaker, & Lafrentz, 2014). For