The Global Epidemiology of Impetigo: A Systematic Review of the Population Prevalence of Impetigo and Pyoderma.
The Global Epidemiology of Impetigo: A Systematic Review of the Population Prevalence of Impetigo and Pyoderma.
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DOI：
10.1371/journal.pone.0136789
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发表时间：
2015
期刊：
影响因子：
3.7
通讯作者：
Carapetis JR
中科院分区：
文献类型：
--
作者：
Bowen AC;Mahé A;Hay RJ;Andrews RM;Steer AC;Tong SY;Carapetis JR
我们对全球儿童人群的脓疱病和更广泛的脓毒症患病率进行了全面、系统的回顾。系统检索了PubMed中1970年1月1日至2014年9月30日期间发表的关于抗抑郁症或抗抑郁症的研究。两名独立的审查员从每篇关于脓疱病患病率的相关文章中提取数据。涉及89项研究的66篇文章符合我们的纳入标准。根据人口监测，82项研究纳入了145，028名评估为脓毒症或脓疱病的儿童的数据。中位儿童患病率为12.3%（IQR 4.2 - 19.4%）。58项（65%）研究来自低收入或中低收入国家，儿童患病率中位数分别为8.4%（IQR 4.2 - 16.1%）和14.5%（IQR 8.3 - 20.9%）。然而，来自高收入国家边缘化社区的贫困儿童的负担最高;中位患病率为19.4%（IQR 3.9 - 43.3%）。根据2000年以来发表的低收入和中低收入国家的研究数据，我们估计，全球任何时候患有小儿麻痹症的儿童人数都超过1.62亿，主要是在热带、资源贫乏的环境中。脓疱病是一种未被充分认识的疾病，与疥疮一起，构成了一种主要的儿童皮肤病，如果不治疗，可能导致终身后果。
We conducted a comprehensive, systematic review of the global childhood population prevalence of impetigo and the broader condition pyoderma. PubMed was systematically searched for impetigo or pyoderma studies published between January 1 1970 and September 30 2014. Two independent reviewers extracted data from each relevant article on the prevalence of impetigo. Sixty-six articles relating to 89 studies met our inclusion criteria. Based on population surveillance, 82 studies included data on 145,028 children assessed for pyoderma or impetigo. Median childhood prevalence was 12·3% (IQR 4·2–19·4%). Fifty-eight (65%) studies were from low or low-middle income countries, where median childhood prevalences were 8·4% (IQR 4·2–16·1%) and 14·5% (IQR 8·3–20·9%), respectively. However, the highest burden was seen in underprivileged children from marginalised communities of high-income countries; median prevalence 19·4%, (IQR 3·9–43·3%). Based on data from studies published since 2000 from low and low-middle income countries, we estimate the global population of children suffering from impetigo at any one time to be in excess of 162 million, predominantly in tropical, resource-poor contexts. Impetigo is an under-recognised disease and in conjunction with scabies, comprises a major childhood dermatological condition with potential lifelong consequences if untreated.