Transovarial transmission of murine typhus rickettsiae in Xenopsylla cheopis fleas.
Transovarial transmission of murine typhus rickettsiae in Xenopsylla cheopis fleas.
复制标题
鼠斑疹伤寒立克次体在印鼠客蚤中的跨卵巢传播。
DOI：
10.1126/science.3966162
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发表时间：
1985
期刊：
影响因子：
--
通讯作者：
Baqar,S
中科院分区：
文献类型：
--
作者：
Farhang-Azad,A;Traub,R;Baqar,S
人们普遍认为，受感染的跳蚤不会将莫瑟立克次体或任何其他已知的病原体传给其后代。据报道，这种经卵巢传播确实发生在实验室感染的印客蚤中。通过直接荧光抗体检测，在感染跳蚤的血淋巴细胞中观察到莫氏立克次体。由其饲养的一代中，多达 11% 的成虫和 2.9% 的幼虫患有明显的立克次体。此外，成批的 F1 跳蚤能够将感染传播给它们所感染的 18% 以上的老鼠。这些数据支持这样的论点，即鼠斑蚤在自然界中大鼠斑疹伤寒的维持中发挥重要作用。
It has been generally accepted that infected fleas do not pass onRickettsia mooseri, or indeed any other known pathogen, to their progeny. It is reported here that such transovarial transmission does occur in laboratory-infectedXenopsylla cheopisfleas. By means of the direct fluorescent antibody test,Rickettsia mooseriwas observed in cells of the hemolymph of infected fleas. As many as 11 percent of the adults and 2.9 percent of the larvae of the generation reared therefrom, had demonstrable rickettsiae. Moreover, batches of the F1fleas were capable of transmitting the infection to more than 18 percent of the rats they infested. The data support the contention thatXenopsylla cheopisfleas play an important role in the maintenance of murine typhus in rats in nature.