"Schizoaffective disorder": an invalid diagnosis? A comparison of schizoaffective disorder, schizophrenia, and affective disorder.

"Schizoaffective disorder": an invalid diagnosis? A comparison of schizoaffective disorder, schizophrenia, and affective disorder.
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“分裂情感障碍”:诊断无效?

DOI:
10.1176/ajp.137.8.921
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发表时间:
1980
期刊:
The American journal of psychiatry
影响因子:
--
通讯作者:
Axelrod,DT
Axelrod,DT
中科院分区:
--
文献类型:
--
作者:
PopeJr,HG;Lipinski,JF;Cohen,BM;Axelrod,DT

文献摘要

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作者将符合躁狂型分裂情感性障碍广泛接受诊断标准的患者与符合躁狂和精神分裂症严格诊断标准的患者进行比较,采用三种验证方法:家族史、短期治疗反应和长期结果。躁狂症患者与分裂情感性障碍患者之间无显著差异。然而,精神分裂症患者与躁狂障碍和分裂情感性障碍患者之间存在一致且通常非常显著的差异。研究结果表明,分裂情感障碍,目前的定义,并不是一个有效的和独立的实体。作者认为,不能诊断为躁狂抑郁症或精神分裂症的精神障碍,没有明显的有机基础,最好被称为“未诊断”或“非典型”精神病。此外,虽然对精神分裂症或躁狂抑郁症的新诊断或分型的建议应该得到鼓励,但在被接受用于临床应用之前,这些建议应该经过严格的有效性筛选。
The authors compared patients meeting widely accepted criteria for the diagnosis of schizoaffective disorder, manic type, with patients meeting rigorous criteria for manic disorder and schizophrenia, using three methods of validation: family history, short-term treatment response, and long-term outcome. No significant differences were found between patients with manic disorder and schizoaffective disorder. However, consistent and often highly significant differences separated patients with schizophrenia from those with manic disorder and schizoaffective disorder. The findings suggest that schizoaffective disorder, as currently defined, is not a valid and independent entity. The authors suggest that psychotic disorders not diagnosable as manic-depressive illness or schizophrenia and without apparent organic basis would best be called" undiagnosed" or" atypical" psychosis. Further, while proposals for new diagnoses or for subtyping of schizophrenia or manic-depressive illness should be encouraged, these should undergo rigorous screening for validity before being accepted into clinical use.