Electromagnetic-Based Deformation Monitoring for PANI-CA Breath Acetone Sensors
Electromagnetic-Based Deformation Monitoring for PANI-CA Breath Acetone Sensors
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DOI：
10.1109/jerm.2022.3205847
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发表时间：
2022-12
影响因子：
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通讯作者：
Balaji Dontha;Michael Faltas;P. Gouma;A. Kiourti
中科院分区：
文献类型：
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作者：
Balaji Dontha;Michael Faltas;P. Gouma;A. Kiourti
我们报告了一种新的基于电磁（EM）的机制，用于量化PANI-CA化学致动器中的弯曲，该致动器检测呼吸丙酮并在体外设置的概念验证中验证可行性。呼吸丙酮是人体代谢的生物标志物，但之前报道的技术是侵入性的、非连续的和/或在高温下操作。为了克服这些限制，我们依赖于先前报道的聚苯胺和醋酸纤维素（PANI-CA）化学致动器，已知其响应于呼吸丙酮水平而弯曲高达30°（即，高达1250 ppm）。我们的方法包括放置在附近的谐振回路，以及嵌入在4 cm × 3 mm的PANI-CA条，并在室温下工作。为了最大限度地减少对带材机械性能的影响，在轻质导电线上实现了环。使用法拉第定律作为条带变形和环未对准，传感器被示出以检测限监测丙酮顶空浓度，实验分辨率为26.1 ppm，通过插值为1 ppm。我们还证明，我们的EM机制与PANI-CA条结合：（a）适用于丙酮传感高达2610 ppm（70°屈曲），与呼吸以外的其他应用相关，（B）可以修改，以监测高达170°的变形，未来将实现更灵敏的化学致动条。该技术可以集成到可穿戴设备中，例如面罩或口衔片。丙酮生物标志物的个性化、非侵入性和连续感测可以支持各种健康诊断的监测，例如脂肪代谢、体重减轻和酮症。
We report a novel electromagnetic (EM) based mechanism for quantifying bending in PANI-CA chemo-actuators that detect breath acetone and validate feasibility in a proof-of-concept in vitro setup. Breath acetone serves as a biomarker of human metabolism, yet previously reported techniques are invasive, non-continuous, and/or operate at high temperatures. To overcome these limitations, we rely on previously reported polyaniline and cellulose acetate (PANI-CA) chemo-actuators that are known to flex up to 30° in response to breath acetone levels (i.e., up to 1250 ppm) in a reversible process. Our approach comprises of resonant loops placed in proximity to as well as embedded in 4 cm × 3 mm PANI-CA strips and operates at room temperature. To minimize impact to the strip's mechanical performance, loops are realized on lightweight conductive threads. Using Faraday's law as the strip deforms and the loops misalign, the sensor is shown to monitor acetone-headspace concentration at a limit of detection and resolution of 26.1 ppm experimentally and 1 ppm through interpolation. We also demonstrate that our EM mechanism in conjunction with PANI-CA strips: (a) is suitable for acetone sensing up to 2610 ppm (70° flexion) relevant to other applications beyond breath, and (b) can be modified to monitor deformation of up to 170° shall more sensitive chemo-actuating strips be implemented in the future. This technology can be integrated into a wearable device for-instance mask or mouthpiece. Personalized, non-invasive and continuous sensing of acetone biomarker can bolster monitoring of various health diagnostics, such as fat-metabolism, weight loss, and ketosis.