A nanoparticle-preparation kit using ethylene glycol-based block copolymers with a common temperature-responsive block

A nanoparticle-preparation kit using ethylene glycol-based block copolymers with a common temperature-responsive block
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使用乙二醇基嵌段共聚物和通用温度响应嵌段的纳米颗粒制备套件

DOI:
10.1039/c7py01541k
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发表时间:
2017
期刊:
影响因子:
4.6
通讯作者:
Aoyagi Takao
Aoyagi Takao
中科院分区:
化学2区
文献类型:
--
作者:
Kotsuchibashi Yohei;Lee Chun Man;Constantinescu Iren;Takeuchi Lily E.;Vappala Sreeparna;Kizhakkedathu Jayachandran N.;Narain Ravin;Ebara Mitsuhiro;Aoyagi Takao

文献摘要

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开发了一种纳米颗粒制备试剂盒系统,用于使用具有常见温度响应性嵌段的基于乙二醇的嵌段共聚物生产所需的纳米颗粒。发现注射的纳米颗粒在肿瘤组织中积聚,并显示出高的血液生物相容性。
A nanoparticle-preparation kit system for producing desired nanoparticles using ethylene glycol-based block copolymers with a common temperature-responsive block was developed. The injected nanoparticles were found to accumulate in the tumor tissue and showed high blood biocompatibility.