Levodopa increases speed of alternating movements in Parkinson’s disease patients
Levodopa increases speed of alternating movements in Parkinson’s disease patients
复制标题
左旋多巴可提高帕金森病患者交替运动的速度
DOI：
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发表时间：
2013
影响因子：
3.3
通讯作者：
A. Harati
中科院分区：
文献类型：
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作者：
T. Müller;S. Peters;A. Harati
交替运动执行障碍是帕金森病（PD）患者的特征性临床体征。目的是比较仪器测量的diadochokinetic运动系列进行之前和1小时后，标准化左旋多巴摄入量和相关的设备结果与各自的评级评分的PD患者。应用左旋多巴后，最大速度和间期改善。两个评估时刻之间的运动幅度没有差异。在服用左旋多巴之前，评级和舒张功能测定仪结果之间出现了更密切的相关性。
Disturbances of alternating movement execution are a characteristic clinical sign of patients with Parkinson’s disease (PD). Objectives were to compare instrumentally measured diadochokinetic motion series carrying out before and 1 h after standardised levodopa intake and to correlate the device results with the respective rating scores of the PD patients. Maximum velocity and interval improved following levodopa application. The amplitude of motions did not differ between both assessment moments. Closer correlations between rating- and diadochokinesimeter outcomes appeared before levodopa intake.