Adverse drug event trigger tool: a practical methodology for measuring medication related harm

Adverse drug event trigger tool: a practical methodology for measuring medication related harm
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DOI:
10.1136/qhc.12.3.194
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发表时间:
2003-06-01
影响因子:
--
通讯作者:
Resar, RK
Resar, RK
中科院分区:
其他
文献类型:
--
作者:
Rozich, JD;Haraden, CR;Resar, RK

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药物不良事件仍然是医疗事故最常见的单一来源,不断将患者置于受伤的风险之中。这并不意外,因为药物治疗是最常见的医疗干预措施,药物使用是一个高度复杂,多学科,主要是手动的过程。评估药物使用的实际安全性历来是困难的,主要是因为传统的方法,如图表审计和自愿报告的数据已被证明是昂贵的,不敏感的,而且在很大程度上是无效的检测错误的药物管理和药物相关的不良临床事件(ADE)。检测ADE的计算机化方法,采用患者病历中的哨兵词或“触发器”,是有效的,但昂贵,需要定制的软件链接到药房数据库。本文介绍了“触发工具”的使用,这是一种相对低成本和“低技术”的自动化技术改造。与传统的报告方法相比,改进的技术似乎将ADE检测率提高了约50倍。
Adverse drug events continue to be the single most frequent source of healthcare mishaps, continually placing patients at risk of injury. This is not unexpected, given that drug treatment is the most common medical intervention and medication use is a highly complex, multidisciplinary, and largely manual process. Assessing the actual safety of drug use has been historically difficult, mainly because traditional methods such as chart audits and voluntary reporting of data have been shown to be expensive, insensitive, and largely ineffective for detecting mistakes in drug administration and drug related adverse clinical events (ADEs). Computerized methods for detecting ADEs, employing sentinel words or "triggers" in a patient's medical record, are effective but expensive and require customized software linkage to pharmacy databases. This paper describes the use of the "trigger tool", a relatively low cost and "low tech" modification of the automated technique. The adapted technique appears to increase the rate of ADE detection approximately 50-fold over traditional reporting methodologies.