Heart deformation analysis: the distribution of regional myocardial motion patterns at left ventricle.
Heart deformation analysis: the distribution of regional myocardial motion patterns at left ventricle.
复制标题
心脏变形分析：左心室局部心肌运动模式的分布。
DOI：
10.1007/s10554-016-1005-y
复制
发表时间：
2017
期刊：
影响因子：
--
通讯作者：
Carr,JamesC
中科院分区：
文献类型：
--
作者：
Lin,Kai;Meng,Leng;Collins,JeremyD;Chowdhary,Varun;Markl,Michael;Carr,JamesC
本研究的目的是检验心脏变形分析（HDA）能够区分左心室（LV）局部心肌运动模式的假设。研究对象为21名无心血管疾病史的健康志愿者，男15名，女6名。在四腔、两腔和短轴视图上对这些受试者进行电影MRI。用HDA工具测量左室节段性心肌运动指数的变化。通过实验比较了侧壁和隔壁的局部位移、速度、应变和应变率。16个心肌节段的心肌运动指数（21例受试者的平均值）存在显著差异（CoV = 18.0-72.4%）。在左室外侧区和间隔区测量的位移、速度、应变和应变率之间存在显著差异（p < 0.05）。总之，HDA能够从多个方面呈现健康志愿者不同的左室局部运动模式。
The aim of the present study was to test the hypothesis that heart deformation analysis (HDA) is able to discriminate regional myocardial motion patterns on the left ventricle (LV). Totally 21 healthy volunteers (15 men and 6 women) without documented cardiovascular diseases were recruited. Cine MRI was performed on those subjects at four-chamber, two-chamber, and short-axis views. The variations of segmental myocardial motion indices of the LV, which were measured with the HDA tool, were investigated. Regional displacement, velocity, strain and strain rate were compared between lateral wall and septal wall usingttests. There are significant variations (CoV = 18.0–72.4%) of myocardial motion indices (average over 21 subjects) among 16 myocardial segments. There are significant differences (p < 0.05) between displacement, velocity, strain and strain rate measured at lateral and septal areas of the LV. In conclusion, HDA is able to present different regional LV motion patterns from multiple aspects in healthy volunteers.