The Effects of Misclassification on the Bias in the Difference Between Two Proportions and the Relative Odds in the Fourfold Table

The Effects of Misclassification on the Bias in the Difference Between Two Proportions and the Relative Odds in the Fourfold Table
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错误分类对四重表中两个比例之间的差异和相对赔率的偏差的影响

DOI:
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发表时间:
1975
期刊:
影响因子:
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通讯作者:
J. Goldberg
J. Goldberg
中科院分区:
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文献类型:
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作者:
J. Goldberg

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摘要 在其他文献[15]中表明,与医学筛查技术相关的假阴性率和假阳性率并不遵循任何通用或简单的模型;并且为分析目的所做的常规假设不成立。研究了2×2列联表中合理且实际的错误分类水平对两个比例之差的偏差、相对优势比的偏差以及这些统计量分布的影响。在两个样本问题中,假阳性率,尤其是它们之间的差异,是错误分类导致的大部分偏差的原因。
Abstract It is shown elsewhere [15] that the false negative and false positive rates associated with medical screening techniques do not follow any general or simple models; and that the usual assumptions made for analytical purposes are violated. The effects of reasonable and actual levels of misclassification in the 2 × 2 table on the bias in the difference between two proportions and on the bias in relative odds as well as on the distributions of these statistics are examined. The false positive rates, and in particular the difference between them, in the two sample problem are responsible for most of the bias resulting from misclassification.