Adenovirus-Extracellular Protein Interactions and Their Impact on Innate Immune Responses by Human Mononuclear Phagocytes.
Adenovirus-Extracellular Protein Interactions and Their Impact on Innate Immune Responses by Human Mononuclear Phagocytes.
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DOI:
10.3390/v12121351
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发表时间:
2020-11-26
期刊:
影响因子:
--
通讯作者:
Kremer EJ
中科院分区:
文献类型:
--
作者:
Chéneau C;Kremer EJ
The aim of this review is to highlight how, in a syngeneic system, human mononuclear phagocytes respond to environments containing human adenovirus (HAdV) and soluble extracellular proteins that influence their innate immune response. Soluble extracellular proteins, including immunoglobulins, blood clotting factors, proteins of the complement system, and/or antimicrobial peptides (AMPs) can exert direct effects by binding to a virus capsid that modifies interactions with pattern recognition receptors and downstream signaling. In addition, the presence, generation, or secretion of extracellular proteins can indirectly influence the response to HAdVs via the activation and recruitment of cells at the site of infection.
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DOI:
10.1038/mt.2015.194
发表时间:
2016-02
期刊:
Molecular therapy : the journal of the American Society of Gene Therapy
影响因子:
--
作者:
Alonso-Padilla J;Papp T;Kaján GL;Benkő M;Havenga M;Lemckert A;Harrach B;Baker AH
通讯作者:
Baker AH
影响因子:
4.4
作者:
De la Rosa, Gonzalo;Yang, De;Oppenheim, Joost J.
通讯作者:
Oppenheim, Joost J.
影响因子:
5.4
作者:
Eichholz, Karsten;Mennechet, Franck J. D.;Kremer, Eric J.
通讯作者:
Kremer, Eric J.
影响因子:
5.1
作者:
Cichon, G;Boeckh-Herwig, S;Burger, R
通讯作者:
Burger, R
影响因子:
168.9
作者:
Buchbinder, Susan P.;Mehrotra, Devon V.;Duerr, Ann;Fitzgerald, Daniel W.;Mogg, Robin;Li, David;Gilbert, Peter B.;Lama, Javier R.;Marmor, Michael;del Rio, Carlos;McElrath, M. Juliana;Casimiro, Danilo R.;Gottesdiener, Keith M.;Chodakewitz, Jeffrey A.;Corey, Lawrence;Robertson, Michael N.
通讯作者:
Robertson, Michael N.