Screening for Retinopathy of Prematurity in a Tertiary Hospital in Istanbul: Incidence and Risk Factors
Screening for Retinopathy of Prematurity in a Tertiary Hospital in Istanbul: Incidence and Risk Factors
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DOI：
10.3928/01913913-20110208-01
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发表时间：
2012-01-01
影响因子：
1.2
通讯作者：
Yetik, Huseyin
中科院分区：
文献类型：
--
作者：
Akcakaya, Aylin Ardagil;Yaylali, Sevil Ari;Yetik, Huseyin
目的：研究伊斯坦布尔某三级医院早产儿视网膜病变（ROP）的发生率及危险因素。方法：回顾性分析2007年4月至2009年9月婴幼儿ROP筛查资料。记录可能的危险因素和眼科检查，并采用卡方检验、单因素和多因素回归进行分析。结果：纳入研究的517例婴儿中，有177例（34.3%）检出ROP；轻度ROP 64例（77.4%），重度ROP 38例（22.6%）。接受ROP治疗的患者平均胎龄和出生体重分别为28.6 +/- 2.3和1143.5 +/- 337.4。其中两名婴儿的胎龄为32克或以上，三名婴儿的出生体重为1500克或以上。多变量回归分析显示胎龄、出生体重、败血症、呼吸窘迫综合征和氧疗时间是ROP的独立预测因子。结论：本研究中观察到的ROP发生率高于发达国家，且患儿相对成熟。包括胎龄小于34周或出生体重小于2000克的标准可以确定所有有风险的婴儿。
Purpose: To study the incidence and risk factors of retinopathy of prematurity (ROP) in premature infants examined in a tertiary hospital in Istanbul.Methods: Data of infants screened for ROP from April 2007 to September 2009 were retrospectively reviewed. Possible risk factors and eye examinations were recorded and analyzed using the chi-square test and univariate and multivariate regressions.Results: ROP was detected in 177 (34.3%) of the 517 infants enrolled in the study; 64 had mild ROP (77.4%) and 38 had severe ROP (22.6%). The mean gestational age and birth weight of patients who were treated for ROP were 28.6 +/- 2.3 and 1,143.5 +/- 337.4, respectively. Two of these infants had a gestational age of 32 g or greater and three had a birth weight of 1,500 g or greater. The multivariate regression analyses showed gestational age, birth weight, sepsis, respiratory distress syndrome, and length of oxygen therapy as independent predictors of ROP.Conclusion: The incidence of ROP observed in this study was higher than that in developed countries and relatively more mature infants were affected. Criteria including gestational age of less than 34 weeks or birth weight of less than 2,000 g would have identified all infants who were at risk.