Social cognition in premotor and parietal cortex
Social cognition in premotor and parietal cortex
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DOI：
10.1080/17470910701434610
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发表时间：
2008-09-01
影响因子：
2
通讯作者：
Iriki, Atsushi
中科院分区：
文献类型：
--
作者：
Fujii, Naotaka;Hihara, Sayaka;Iriki, Atsushi
正确的社会行为需要不断观察社会环境。几秒钟前合适的行为不一定现在就合适。大脑将目光集中在当前的社会空间上，并不断更新其对环境和社会背景的内部表征。监控他人的行为对于这种更新至关重要。参与感知他人行为的神经系统已被广泛探索，但在单细胞水平上对该系统的详细定量特征仍知之甚少。为了解决这个问题，我们使用了新的多维记录技术，记录神经元活动的同时，从腹侧运动前皮层（PM）和顶叶皮层在左半球的猴子，而他们执行的食物抓取任务。35%（52/148）的PM神经元和54%（94/174）的顶叶神经元显示出运动相关（MR）反应，这意味着它们的活性在对自己和/或他人的手臂运动的各种组合的反应中增加。这两个领域都表现出强烈的偏侧偏好自我正确的行动。当识别另一只猴子的动作时，PM-MR神经元表现出与自我动作相同的右臂偏好，而顶叶-MR神经元则没有表现出手臂偏好。虽然这两个区域都能区分自我行动，但PM-MR神经元的比例要大得多。这些结果表明，PM神经元提供信息的动作的代理人和效应器的动作认知内的镜像神经元网络的原语，而顶叶神经元代表社会空间，并参与识别另一个代理人的行动，在一个人自己的行动在顶叶-前额叶网络。
Socially correct behavior requires constant observation of the social environment. Behavior that was appropriate a few seconds ago is not guaranteed to be appropriate now. The brain keeps the eyes focused on the current social space and constantly updates its internal representation of the environment and social context. Monitoring the behavior of others is essential for this updating. The neural systems involved in perceiving the actions of others have been explored extensively, but the detailed, quantitative character of the system at the single-cell level remains poorly understood. To address this question, we used the new technique of multidimensional recording to record neuronal activity in monkeys simultaneously from ventral premotor cortex (PM) and parietal cortex in the left hemisphere while they performed a food grab task. Motion-related (MR) response was shown by 35% (52/148) of PM neurons and 54% (94/174) of parietal neurons, meaning their activity increased in response to various combinations of arm motions made by self and/or other. Both areas showed robust lateralized preference to Self-Right action. When it came to recognizing the actions of the other monkey, PM-MR neurons showed the same kind of right-arm preference as self-action while parietal-MR neurons, in contrast, did not show arm preference. And while both areas discriminated self-action front other, a significantly larger proportion of PM-MR neurons did so. These results suggest that PM neurons provide information about an action's agent and effector as primitives of action cognition within the mirror neuron network, while parietal neurons represent social space and participate in the recognition of another agent's actions in relation to one's own actions within the parieto-prefrontal network.