CHONDROBLASTOMA - A CLINICAL AND RADIOLOGICAL STUDY OF 104 CASES
CHONDROBLASTOMA - A CLINICAL AND RADIOLOGICAL STUDY OF 104 CASES
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DOI：
10.1007/bf00361187
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发表时间：
1985-01-01
影响因子：
2.1
通讯作者：
MULDER, JD
中科院分区：
文献类型：
--
作者：
BLOEM, JL;MULDER, JD
本文报告了104例软骨母细胞瘤患者的临床和影像学表现。疼痛几乎是一种持续存在的症状，在关节旁病变的情况下，通常伴有邻近关节功能受损。大多数（80%）是长骨，平均发病年龄为16岁。这些病变的特征性影像学表现为偏心性透亮线，边缘清晰，约三分之一的病例含有钙化区。它们总是与生长板有关。近一半局限于受影响的骨骺或骨突本身，但其余大部分穿过生长板，也涉及相邻的干骺端。好发部位为膝关节周围骨、肱骨近端和股骨近端。少数（20%）影响扁骨和短管状骨的手和脚，一个特殊的亲和力跟骨和距骨。平均发病年龄为28岁。放射学模式相似，除了受影响的骨更倾向于扩张。并发症包括16例（其中10例发生在长骨）继发性骨囊肿形成，1例恶性软骨母细胞瘤，1例原始软骨母细胞瘤放射后发生纤维肉瘤。
The clinical and radiographic findings in 104 patients with chondroblastoma are presented. Pain was an almost constant presenting complaint, often accompanied in the case of para-articular lesions by impaired function of an adjacent joint. The majority (80%) were in long bones with a mean age of presentation of 16 years. The characteristic radiological image of these lesions was an eccentric radiolucency, having a sharply defined sclerotic margin and containing areas of calcification in approximately a third of cases. They were always related to a growth plate. Nearly half were confined to the affected epiphysis or apophysis itself, but most of the remainder had traversed the growth plate to involve also the adjacent metaphysis. The bones around the knee and the proximal ends of the humerus and femur were the sites of predilection. A minority (20%) affected flat bones and short tubular bones of the hand and foot, with a peculiar affinity for the calcaneus and talus. The mean age of presentation of these was 28 years. The radiological pattern was similar, except for a greater tendency to expand the affected bone. Complications included the formation of a secondary aneurysmal bone cyst in 16 cases (10 of them in long bones), one malignant chondroblastoma, and one fibrosarcoma developing after radiation of the original chondroblastoma.