Stereoselective synthesis of 3-alkylideneoxindoles via palladium-catalyzed domino reactions

Stereoselective synthesis of 3-alkylideneoxindoles via palladium-catalyzed domino reactions
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DOI:
10.1021/jo0508604
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发表时间:
2005-08-19
影响因子:
3.6
通讯作者:
Takemoto, Y
Takemoto, Y
中科院分区:
化学2区
文献类型:
--
作者:
Yanada, R;Obika, S;Takemoto, Y

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[图表]我们已经开发了有效的催化方法,用于通过钯催化的Heck/Suzuki-Miyaura,Heck/Heck和Heck/羰基化/Suzuki-Miyaura多米诺反应立体选择性和多样性合成各种(E)-,(Z)-和二取代的3-亚烷基羟吲哚和3-亚烷基-苯并呋喃-2-酮。
[GRAPHICS]We have developed efficient catalytic methods for the stereoselective and diversity synthesis of various (E)-, (Z)-, and disubstituted 3-alkylideneoxindoles and 3-alkylidene-benzofuran-2-ones via palladium-catalyzed Heck/Suzuki-Miyaura, Heck/Heck, and Heck/carbonylation/Suzuki-Miyaura domino reactions.