Living Donor Kidney Transplantation in a Patient With Epidermolysis Bullosa: A Case Report
Living Donor Kidney Transplantation in a Patient With Epidermolysis Bullosa: A Case Report
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DOI：
10.1016/j.transproceed.2019.04.049
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发表时间：
2019-11-01
影响因子：
0.9
通讯作者：
Minnee, R. C.
中科院分区：
文献类型：
--
作者：
Ceuppens, S. H. E.;Kimenai, H. J. A. N.;Minnee, R. C.
严重隐性营养不良性大疱性表皮病是一种非常罕见的遗传性疾病，从出生开始就形成过多的水泡。在这一人群中进行手术干预是一个挑战：在处理先前瘢痕组织的同时防止新病变的形成。我们报告一位27岁的末期肾病患者，因快速进行性伊加肾病而引发。活体供肾移植是在局麻、腰麻和硬膜外麻醉下进行的，对患有终末期肾病的大疱性表皮病患者进行活体供肾移植，不应成为移植的禁忌证，应在精心准备后，将其作为一种可行的、可行的选择。
Severe recessive dystrophic epidermolysis bullosa is a very rare inherited disease with excessive blisters forming starting at birth. Surgical intervention in this population creates a challenge: preventing formation of new lesions while managing previously scarred tissues. We present a case of a 27-year-old patient with end-stage renal disease caused by rapidly progressive IgA nephropathy. Living donor kidney transplantation was performed under local, spinal and epidural anesthesia.Living kidney transplantation in epidermolysis bullosa patients with end-stage renal disease should not be a contraindication for transplantation and should be considered as a viable and feasible option after careful preparation.