Clinical outcome of gastric cancer patients with bone marrow metastases
Clinical outcome of gastric cancer patients with bone marrow metastases
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DOI：
10.1159/000127386
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发表时间：
2007-01-01
期刊：
影响因子：
3.5
通讯作者：
Kang, Won Ki
中科院分区：
文献类型：
--
作者：
Kim, Hyo Song;Yi, Seong Yoon;Kang, Won Ki
背景：众所周知，伴有骨髓转移的胃癌具有迅速恶化的临床过程。我们对胃癌骨髓转移患者的临床表现和预后进行了回顾性分析。方法：选择1994年9月至2006年2月经病理证实的39例胃癌骨髓转移患者。结果：患者多表现为年龄偏小、低分化腺癌或印戒细胞癌、血小板减少、贫血、乳酸脱氢酶和碱性磷酸酶升高。预后不良的生存因素是血钠。
Background: Gastric cancer with bone marrow metastases is known to pursue a rapidly deteriorating clinical course. We conducted a retrospective analysis to evaluate clinical manifestations and prognosis of gastric cancer patients with bone marrow metastases. Methods: Between September 1994 and February 2006, 39 gastric cancer patients with pathologically confirmed bone marrow dissemination were selected. Results: The majority of the patients showed younger age, poorly differentiated adenocarcinoma or signet ring cell carcinoma, thrombocytopenia, anemia, elevated lactate dehydrogenase and alkaline phosphatase. Poor prognostic factors for survival were serum sodium