Fast and straightforward in-situ synthesis of gold nanoparticles on a thread-based microfluidic device for application in surface-enhanced Raman scattering detection
Fast and straightforward in-situ synthesis of gold nanoparticles on a thread-based microfluidic device for application in surface-enhanced Raman scattering detection
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DOI：
10.1016/j.microc.2020.104985
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发表时间：
2020-07-01
影响因子：
4.8
通讯作者：
de Jesus, Dosil Pereira
中科院分区：
文献类型：
--
作者：
Adamo, Cristina Battesini;Junger, Ayandra Santos;de Jesus, Dosil Pereira
首次使用形成微流控装置的棉线，使用微量试剂进行了金纳米颗粒(AuNPs)的快速、直接的土耳其合成。根据合成条件的不同，可以得到尺寸在20~40 nm之间的球形AuNPs。在表面增强拉曼散射(SERS)检测结晶紫和尼古丁的过程中，棉线也作为合成的AuNPs的物理载体。烟碱在L 2-6 mg浓度范围内线性关系良好(R2=0.9844)。尼古丁的检出限为0.18mgL-1。该衬底具有成本低、速度快、易于制作等优点，可用于表面增强拉曼散射检测。
Cotton threads forming a microfluidic device were used for the first time to conduct a fast and straightforward Turkevich synthesis of gold nanoparticles (AuNPs) using minute amounts of reagents. Spherical AuNPs were obtained with sizes that varied from 20 to 40 nm, according to the synthesis conditions. The cotton thread also acted as physical support for the synthesized AuNPs during surface-enhanced Raman scattering (SERS) detection of crystal violet and nicotine. A calibration curve for nicotine with acceptable linearity (R-2 = 0.9844) in the concentration range of 2-6 mg L-1 was obtained. The limit of detection for nicotine was 0.18 mg L-1. The proposed substrate was considered cheap, fast, and easy to be fabricated and applied in SERS detection.