Mating stimulation required for mating-induced estrous abbreviation in female rats: Effects of repeated testing
Mating stimulation required for mating-induced estrous abbreviation in female rats: Effects of repeated testing
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DOI：
10.1006/hbeh.2002.1809
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发表时间：
2002-09-01
影响因子：
3.5
通讯作者：
Blaustein, JD
中科院分区：
文献类型：
--
作者：
Bennett, AL;Blasberg, ME;Blaustein, JD
交配刺激，特别是阴道-宫颈刺激，会导致雌性大鼠发情缩短。在之前的大多数研究中，雌性大鼠被反复测试性行为，直到发生发情终止。因此，尚不清楚在重复测试过程中接受的感觉刺激(例如，侧面刺激、嗅觉暗示)是否有助于发情缩写。在实验1中，我们测定了重复试验时，提前两次或四次射精对发情终止率的影响。我们比较了卵巢摘除、激素刺激的雌性大鼠接受(1)四次射精、(2)两次射精或(3)不射精的雌性大鼠。排出两次或四次射精的雌性在12小时后表现出比没有射精的雌性显著更低的性接受水平。这些结果证实了重复测试过程中，重复测试会导致发情期缩写。在实验2中，我们确定了发情缩写是否有必要进行重复测试。去势、荷尔蒙刺激的雌性大鼠被提前两次射精或不提前。然后，对这些老鼠进行重复或仅一次的性行为测试。有先入性行为并反复测试性行为的雌性比没有先入性行为的雌性在性接受方面有统计上的显著下降；然而，当她们只被测试一次时，有先验性行为的雌性的性接受水平与没有先入性行为的雌性没有区别。结果表明，热持续时间是促进性接受能力表达的因素和抑制性接受能力的因素之间复杂相互作用的结果。(C)2002年埃尔塞维尔科学公司(美国)。
Mating stimulation, particularly vaginal-cervical stimulation, causes estrous abbreviation in female rats. In most previous studies, female rats were repeatedly tested for sexual behavior until estrous termination occurred. Thus, it was not clear whether sensory stimulation (e.g., flank stimulation, olfactory cues) received during the repeated testing procedure contributed to estrous abbreviation. In Experiment 1, we determined the effect of premating to two or four ejaculations on the rate of estrous termination when a repeated testing procedure was used. We compared ovariectornized, hormone-primed, female rats receiving (1) four ejaculations, (2) two ejaculations, or (3) no premating. Females premated to either two or four ejaculations showed significantly lower levels of sexual receptivity 12 h later than did non-premated females. These results confirm that premating induces estrous abbreviation when a repeated testing procedure is used. In Experiment 2, we determined whether the repeated testing procedure was necessary for estrous abbreviation. Ovariectomized, hormone-primed female rats were premated to two ejaculations or not premated. The rats were then tested for sexual behavior repeatedly or only once. Females that were premated and repeatedly tested for sexual behavior showed a statistically significant decrease in sexual receptivity compared to females that were not premated; however, the level of sexual receptivity in premated females did not differ from that in non-premated females when they were tested only once. The results suggest that heat duration is the result of a complex interplay between those factors that promote the expression of sexual receptivity and those that inhibit it. (C) 2002 Elsevier Science (USA).