PharmGKB: The Pharmacogenetics Knowledge Base
PharmGKB: The Pharmacogenetics Knowledge Base
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DOI：
10.1093/nar/30.1.163
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发表时间：
2002-01-01
影响因子：
14.9
通讯作者：
Klein, TE
中科院分区：
文献类型：
--
作者：
Hewett, M;Oliver, DE;Klein, TE
药物遗传学知识库（PharmGKB; http：//www.pharmgkb.org/）包含从正在进行的药物遗传学研究中收集的基因组、表型和临床信息。已注册的研究网络成员可使用浏览、查询、下载、提交、编辑和处理信息的工具。这些工具的一个子集是公开的。PharmGKB目前包含超过150个正在研究的基因，14个Coriell种群和一个大型的药物遗传学概念本体。遗传药理学概念和实验数据通过一组关系相互连接，形成遗传药理学研究人员的知识库。PharmGKB中的信息及其处理该信息的相关工具是为前沿药物遗传学研究量身定制的。PharmGKB项目于2000年4月启动，知识库第一版于2001年2月上网。
The Pharmacogenetics Knowledge Base (PharmGKB; http://www.pharmgkb.org/) contains genomic, phenotype and clinical information collected from ongoing pharmacogenetic studies. Tools to browse, query, download, submit, edit and process the information are available to registered research network members. A subset of the tools is publicly available. PharmGKB currently contains over 150 genes under study, 14 Coriell populations and a large ontology of pharmacogenetics concepts. The pharmacogenetic concepts and the experimental data are interconnected by a set of relations to form a knowledge base of information for pharmacogenetic researchers. The information in PharmGKB, and its associated tools for processing that information, are tailored for leading-edge pharmacogenetics research. The PharmGKB project was initiated in April 2000 and the first version of the knowledge base went online in February 2001.