Alternative respiratory pathways in higher plants
Alternative respiratory pathways in higher plants
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高等植物的替代呼吸途径
DOI：
10.1002/9781118789971.ch5
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发表时间：
2015
期刊：
影响因子：
--
通讯作者：
Elliott C
中科院分区：
文献类型：
--
作者：
Elliott C
替代氧化酶 (AOX) 对许多呼吸抑制剂不敏感，这些抑制剂已知会影响呼吸链的其他成分，例如氰化物和抗霉素 A。AOX 普遍存在于所有植物中，并且也存在于其他几种物种中，包括几种人类寄生虫。 AOX 是产热植物和寄生锥虫生存的关键蛋白质。质体末端氧化酶（PTOX）被认为除了在质体电子传递链的组分受到抑制时提供电子传递之外，在类胡萝卜素的去饱和中发挥重要作用。众所周知，AOX 使用泛醇作为氢和电子供体，将氧气还原为水。由于与二铁羧酸盐蛋白和质体末端氧化酶都有祖先关系，AOX 已从一种清除剂进化为一种功能更加多样化的泛醇氧化酶，其核心具有四螺旋束。
Alternative oxidase (AOX) is insensitive to a number of respiratory inhibitors which are known to affect the other components of the respiratory chain such as cyanide and antimycin A. AOX is ubiquitous in all plants, and is also found in several other species – including several human parasites. AOX is a protein key to the survival of both thermogenic plants and parasitic trypanosomes. Plastid terminal oxidase (PTOX) is thought to play an essential role in the desaturation of carotenoids in addition to providing electron transport when components of the plastid electron transport chain are inhibited. Catalytically, AOX is known to reduce oxygen through to water, using ubiquinol as the hydrogen and electron donor. With ancestral relationships to both diiron carboxylate proteins and the plastid terminal oxidase, AOX has evolved from a scavenger to a more functionally diverse ubiquinol oxidase with a four‐helix bundle at its core.