A Two-Photon Fluorescent Probe for Thiols in Live Cells and Tissues
A Two-Photon Fluorescent Probe for Thiols in Live Cells and Tissues
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DOI：
10.1021/ja9090676
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发表时间：
2010-02-03
影响因子：
15
通讯作者：
Cho, Bong Rae
中科院分区：
文献类型：
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作者：
Lee, Jun Han;Lim, Chang Su;Cho, Bong Rae
我们报道了一种双光子荧光探针(ASS)，它可以被780 nm的飞秒脉冲激发，并利用双光子显微镜在90-180微米深度检测活细胞和活组织中的硫醇，而不受其他生物相关物种的干扰。
We report a two-photon fluorescent probe (ASS) that can be excited by 780 nm femtosecond pulses and detect thiols in live cells and living tissues at a 90-180 mu m depth without interference from other biologically relevant species by two-photon microscopy.