Can ultrasonography differentiate anastomotic and non-anastomotic biliary strictures after orthotopic liver transplantation- a single-center experience

Can ultrasonography differentiate anastomotic and non-anastomotic biliary strictures after orthotopic liver transplantation- a single-center experience
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DOI:
10.1016/j.ejrad.2020.109416
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发表时间:
2021-01-01
影响因子:
3.3
通讯作者:
Ren, Jie
Ren, Jie
中科院分区:
医学3区
文献类型:
--
作者:
Liao, Mei;Guo, Huanyi;Ren, Jie

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目的:探讨超声在鉴别原位肝移植(OLT)后吻合性胆管狭窄(AS)和非吻合性胆管狭窄(NAS)中的作用。对76例吻合口狭窄(AS)和103例非吻合口狭窄(NAS)进行分析。参照标准为胆道造影术。结果:AS组与NAS组(P<0.001)对肝内胆管跳跃性、不规则扩张及肝门部胆管腔的显示有显著差异。NAS较好的超声表现为肝门部胆管管腔轮廓显示不佳。其敏感性、特异性和准确性分别为94.2%、84.2%和88.9%。结论:超声对肝移植术后AS和NAS的鉴别诊断是有用和有效的。
Purpose: To evaluate the role of ultrasonography (US) in differentiating anastomotic biliary strictures (AS) and non-anastomotic biliary strictures (NAS) after orthotopic liver transplantation (OLT).Method: This retrospective study included 1259 OLT recipients between 2005-2018. Seventy-six with anastomotic strictures (AS) and 103 with non-anastomotic strictures (NAS) were analyzed. The reference standard was cholangiography. The sensitivity, specificity, accuracy of US was evaluated.Results: There were significant differences between AS and NAS groups (p < 0.001) for skipped and irregular dilatation of intrahepatic bile duct and visualization of hilar biliary lumen. The better US imaging feature for NAS was poorly visualized and non- visible hilar bile duct luminal contour. The sensitivity, specificity and accuracy were 94.2 %, 84.2 % and 88.9 % respectively. Combined two predictors greatly increased the specificity to 93.4 % while diminished its sensitivity and accuracy.Conclusion: US is useful and efficient to differentiate AS and NAS after OLT.