What do different databases tell about the use of opioids in seven European countries in 2002?
What do different databases tell about the use of opioids in seven European countries in 2002?
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DOI：
10.1016/j.ejpain.2007.10.012
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发表时间：
2008-08-01
影响因子：
3.6
通讯作者：
Kalso, Eija
中科院分区：
文献类型：
--
作者：
Hamunen, Katri;Laitinen-Parkkonen, Pirjo;Kalso, Eija
目的：本文的目的是分析阿片类药物的消费在一些欧洲国家使用不同来源的data.Methods：数据摘自联合国国际麻醉品管制局（麻管局）2003年的报告，并从登记册的国家卫生当局在七个国家的数据可用于2002年。阿片类药物的使用量计算为每日每1000名居民的每日限定剂量（DDD/1000/天）。进一步探索了初级保健患者阿片类药物消费特征（年龄、性别、消费的阿片类药物类型）的丹麦药品登记统计。对类阿片消费总量和11种选定类阿片（7种强效和4种弱效）的消费量进行了分析。门诊病人消耗的阿片类药物的量也examined.Results：有相当大的差异，报告的阿片类药物的数量和显着的差异之间的国家数据和麻管局报告的阿片类药物的消费量。国家药物消费登记册的数据来源各不相同（药店或批发）。麻管局的数据提供的信息石油阿片类药物进口和估计需要，而不是医疗consumption.Conclusions：需要谨慎解释的数据时，阿片类药物消费的国家之间的差异，因为收集和报告的数据。需要更好地记录类阿片消费情况，以便对不同国家的类阿片消费及其对疼痛管理的可能影响进行有意义的分析。需要关于癌症相关疼痛与慢性非恶性疼痛相比较的阿片类药物消耗数据。应为所有欧洲国家建立收集止痛药消费数据的统一方法。(C)2007年，国际疼痛研究协会欧洲分会联合会。由爱思唯尔有限公司出版。保留所有权利。
Objective: The objective of this paper was to analyse opioid consumption in a number European countries using different sources of data.Methods: Data were extracted from the United Nations' International Narcotics Control Board Report (INCB) 2003 and from the registers of the national health authorities in seven countries where data were available for 2002. The amount of opioid used was calculated as daily defined doses per 1000 inhabitants per day (DDD/1000/day). Danish Register of Medicinal Products Statistics was further explored for characteristics of opioid consumption (age, gender, type of opioids consumed) by patients in primary care. Total opioid consumption and consumption of 11 selected opioids (7 strong and 4 weak) were analysed. The amount of opioids consumed by outpatients was also examined.Results: There were considerable differences in the number of opioids reported and significant discrepancies in the amounts Of opioids consumed between the national data and the INCB report. The source of data for the national registers on drug consumption varied (pharmacies or wholesale). The INCB data provide information oil opioid import and estimated need rather than on medical consumption.Conclusions: Caution is required when interpreting the data on opioid consumption between countries because of differences in the collection and reporting of data. Better recording of opioid consumption is needed for meaningful analysis of opioid consumption and its possible effect on pain management in different countries. Data on opioids consumed for cancer-related pain in comparison with chronic non-malignant pain are needed. A uniform method of collection of data on analgesic consumption should be established for all European countries. (C) 2007 European Federation of Chapters of the International Association for the Study of Pain. Published by Elsevier Ltd. All rights reserved.