An Automated Method for Assessing Topographical Structure-Function Agreement in Abnormal Glaucomatous Regions
An Automated Method for Assessing Topographical Structure-Function Agreement in Abnormal Glaucomatous Regions
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DOI:
10.1167/tvst.9.4.14
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发表时间:
2020-03-01
影响因子:
3
通讯作者:
Hood, Donald C.
中科院分区:
文献类型:
--
作者:
Tsamis, Emmanouil;Bommakanti, Nikhil K.;Hood, Donald C.
Purpose: To develop an automated/objective method for topographically comparing abnormal regions on optical coherence tomography (OCT) and visual field (VF) tests of eyes with early glaucoma.Methods: A custom R program was developed that allows for both visualization and automatic assessment of the topographical agreement between functional (24-2 and/or 10-2 VF) and structural (widefield OCT retinal nerve fiber layer and/or retinal ganglion cell layer) deviation/probability maps. It was optimized using information from 98 eyes: 53 diagnosed as "definitely glaucoma" (DG) and 45 recruited as healthy (H) controls. Different pairs of abnormal VF (P