Squamous cell carcinoma of the temporal bone: a radiographic-pathologic correlation.
Squamous cell carcinoma of the temporal bone: a radiographic-pathologic correlation.
复制标题
颞骨鳞状细胞癌：放射学病理相关性。
DOI：
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发表时间：
2001
期刊：
影响因子：
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通讯作者：
MD David W. Eisele
中科院分区：
文献类型：
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作者：
MD M. Boyd Gillespie;MD Howard W. Francis;MD Nelson Chee;MD David W. Eisele
目的
评估先前提出的颞骨原发性鳞状细胞癌分期系统的实用性。
方法
回顾性图表审查15例患者治疗的鳞状细胞癌的颞骨超过13年的时间在学术三级转诊中心。通过对医疗和手术记录、影像学研究和手术病理学报告的审查，对匹兹堡大学的分期系统进行了评价。对13例随访超过24个月的患者进行结局分析。
结果
根据匹兹堡大学分期系统，15例中有11例（73%）的放射学和手术病理分期相关。影像学分期系统对较大（T3/T4）肿瘤比较小（T1/T2）肿瘤更准确（83% vs 67%）。与没有疾病证据的患者相比，死亡者更可能出现耳痛（67%对43%），面神经麻痹（33%对0%）和T3/T4肿瘤（100%对14%）。
结论
匹兹堡大学分期系统的病理分期与患者预后密切相关，比术前放射学分期更敏感。颞骨鳞状细胞癌的预后很大程度上取决于发病时局部病变的程度。
OBJECTIVE
To assess the utility of a previously proposed staging system for patients with primary squamous cell carcinoma of the temporal bone.
METHODS
Retrospective chart review of 15 patients treated for squamous cell carcinoma of the temporal bone over a 13-year period at an academic tertiary referral center. A review of the medical and surgical records, radiographic studies, and surgical pathology reports allowed for an evaluation of the University of Pittsburgh staging system. Outcome analysis was performed on 13 patients with more than 24 months of follow-up.
RESULTS
Radiographic and surgical pathology staging according to the University of Pittsburgh staging system correlated in 11 (73%) of 15 cases. The radiographic staging system was more accurate for larger (T3/T4) tumors than for smaller (T1/T2) tumors (83% vs 67%). When compared with patients with no evidence of disease, nonsurvivors were more likely to present with otalgia (67% vs 43%), facial nerve paralysis (33% vs 0%), and T3/T4 tumors (100% vs 14%).
CONCLUSIONS
Pathologic staging by the University of Pittsburgh staging system closely correlates with patient outcome and is more sensitive than preoperative radiographic staging. Prognosis in squamous cell carcinoma of the temporal bone is largely determined by the extent of local disease at the time of presentation.