Retrosplenial cortex and its role in spatial cognition.
Retrosplenial cortex and its role in spatial cognition.
复制标题
DOI：
10.1177/2398212818757098
复制
发表时间：
2018
影响因子：
--
通讯作者：
Nelson AJD
中科院分区：
文献类型：
--
作者：
Mitchell AS;Czajkowski R;Zhang N;Jeffery K;Nelson AJD
压后皮质是后新皮质系统内的一个区域，与一系列大脑网络（皮质和皮质下）紧密相连，即参与无数的认知任务。虽然对于它的确切功能还没有达成共识，但来自人类和动物研究的证据清楚地指出了它在空间认知中的作用。然而，空间处理功能障碍后，压后皮质损伤是不直接的，导致难以确定其作用的确切性质。在这篇文章中，我们回顾了这些文献，并将已提出的想法类型分为三个广泛的，有些重叠的类别：（1）学习地标位置，稳定性和持久性;（2）空间参考框架之间的整合;（3）巩固和检索空间知识（图式）。我们评估这些模型，并建议如何测试它们，然后简要讨论空间功能是否可能是情景记忆中更一般功能的一个子集。
Retrosplenial cortex is a region within the posterior neocortical system, heavily interconnected with an array of brain networks, both cortical and subcortical, that is, engaged by a myriad of cognitive tasks. Although there is no consensus as to its precise function, evidence from both human and animal studies clearly points to a role in spatial cognition. However, the spatial processing impairments that follow retrosplenial cortex damage are not straightforward to characterise, leading to difficulties in defining the exact nature of its role. In this article, we review this literature and classify the types of ideas that have been put forward into three broad, somewhat overlapping classes: (1) learning of landmark location, stability and permanence; (2) integration between spatial reference frames; and (3) consolidation and retrieval of spatial knowledge (schemas). We evaluate these models and suggest ways to test them, before briefly discussing whether the spatial function may be a subset of a more general function in episodic memory.