Randomized controlled trial of a nurse-led rheumatology clinic for monitoring biological therapy.
Randomized controlled trial of a nurse-led rheumatology clinic for monitoring biological therapy.
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DOI：
10.1111/jan.12183
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发表时间：
2014-01
影响因子：
3.8
通讯作者：
Bergman S
中科院分区：
文献类型：
--
作者：
Larsson I;Fridlund B;Arvidsson B;Teleman A;Bergman S
比较和评估由护士领导的风湿科诊所和由风湿科医生领导的诊所对疾病活动度低或正在接受生物治疗的缓解期患者的治疗结果。用生物疗法治疗慢性炎症性关节炎的患者通常由风湿科医生监测。建议由护士领导的风湿病诊所适用于疾病活动度低或病情缓解的患者。随机对照试验。在2009年10月至2011年8月期间进行了一项为期12个月的随访试验，其中107名患者被随机分为两组，一组是护士领导的以人为本的风湿病诊所(干预组；n=653)，另一组是风湿病医生领导的诊所(对照组；n=854)。假设在12个月的随访中，护士领导的临床结果不会比风湿病医生领导的诊所的结果差。主要结果是疾病活动度通过疾病活动度评分28来衡量。干预组47名患者和对照组50名患者完成了为期12个月的试验。试验表明，在疾病活动评分28分的平均变化、疼痛视觉模拟量表、健康评估问卷、对获得风湿病治疗的满意度或信心方面，两组之间没有统计学上的显著差异。接受生物治疗的稳定期慢性炎症性关节炎患者可以由护士领导的风湿病诊所进行监测，根据疾病活动评分28分衡量，结果没有差异。
To compare and evaluate the treatment outcomes of a nurse-led rheumatology clinic and a rheumatologist-led clinic in patients with low disease activity or in remission who are undergoing biological therapy. Patients with chronic inflammatory arthritis treated with biological therapy are usually monitored by rheumatologists. Nurse-led rheumatology clinics have been proposed in patients with low disease activity or in remission. Randomized controlled trial. A 12-month follow-up trial was conducted between October 2009 and August 2011, where 107 patients were randomized into two groups with a 6-month follow-up to a nurse-led rheumatology clinic based on person-centred care (intervention group; n = 53) or to a rheumatologist-led clinic (control group; n = 54). The hypothesis was that the nurse-led clinic outcomes would not be inferior to those obtained from a rheumatologist-led clinic at the 12-month follow-up. The primary outcome was disease activity measured by Disease Activity Score 28. A total of 47 patients in the intervention group and 50 in the control group completed the 12-month trial. The trial revealed no statistically significant differences between groups in mean change of Disease Activity Score 28, Visual Analogue Scales for pain, the Health Assessment Questionnaire, satisfaction with or confidence in obtaining rheumatology care. Patients with stable chronic inflammatory arthritis undergoing biological therapy could be monitored by a nurse-led rheumatology clinic without difference in outcome as measured by the Disease Activity Score 28.
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影响因子：
--
作者：
Glintborg, Bente;Ostergaard, Mikkel;Hetland, Merete Lund
通讯作者：
Hetland, Merete Lund
影响因子：
27.4
作者：
Fransen, J.;Antoni, C.;Van Riel, P. L. C. M.
通讯作者：
Van Riel, P. L. C. M.
影响因子：
2.3
作者：
Eriksen, Kirk;Rochester, Roderic P.;Hurwitz, Eric L.
通讯作者：
Hurwitz, Eric L.
影响因子：
4.9
作者：
Vander Cruyssen B;Van Looy S;Wyns B;Westhovens R;Durez P;Van den Bosch F;Veys EM;Mielants H;De Clerck L;Peretz A;Malaise M;Verbruggen L;Vastesaeger N;Geldhof A;Boullart L;De Keyser F
通讯作者：
De Keyser F
DOI：
10.1136/bmj.c3995
发表时间：
2010-08-23
期刊：
BMJ (Clinical research ed.)
影响因子：
--
作者：
Clark CE;Smith LF;Taylor RS;Campbell JL
通讯作者：
Campbell JL