CT Perfusion Imaging in Acute Stroke
CT Perfusion Imaging in Acute Stroke
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DOI：
10.1016/j.nic.2011.01.008
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发表时间：
2011-05-01
影响因子：
2.3
通讯作者：
Lev, Michael H.
中科院分区：
文献类型：
--
作者：
Konstas, Angelos A.;Wintermark, Max;Lev, Michael H.
计算机断层扫描灌注（CTP）成像是一种先进的方式，可提供有关脑实质毛细血管水平血流动力学的重要信息。CTP可以通过澄清急性脑生理学和血液动力学状态来帮助急性中风患者的诊断、管理和预后，包括区分严重灌注不足但可能可挽救的组织与可能不可逆梗死的组织（“核心”）和灌注不足但代谢稳定的组织（“良性低血”）。通常需要对缺血的存在和程度进行定性估计以指导临床管理。辐射剂量问题与CTP成像，目前关注的一个话题，也在这次审查中得到解决。
Computed tomographic perfusion (CTP) imaging is an advanced modality that provides important information about capillary-level hemodynamics of the brain parenchyma. CTP can aid in diagnosis, management, and prognosis of acute stroke patients by clarifying acute cerebral physiology and hemodynamic status, including distinguishing severely hypoperfused but potentially salvageable tissue from both tissue likely to be irreversibly infarcted ("core") and hypoperfused but metabolically stable tissue ("benign oligemia"). A qualitative estimate of the presence and degree of ischemia is typically required for guiding clinical management. Radiation dose issues with CTP imaging, a topic of much current concern, are also addressed in this review.