A Newly Synthesized Tris(crown ether) Ionophore for Assisted Ion Transfer at NanoITIES Electrodes
A Newly Synthesized Tris(crown ether) Ionophore for Assisted Ion Transfer at NanoITIES Electrodes
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DOI：
10.1002/celc.201901997
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发表时间：
2020-02-17
期刊：
影响因子：
4
通讯作者：
Shen, Mei
中科院分区：
文献类型：
--
作者：
Chen, Ran;Yang, Anna;Shen, Mei
在两种不混溶电解质溶液（ITIES）之间的移液管支持界面上的辅助离子转移已经成为检测各种离子种类和研究离子络合的重要方法。一个典型的离子载体包含一个离子结合中心，如二苯并-18-冠-6 （DB18C6）。目前尚不清楚离子的检测是如何变化的，当辅助离子载体与多个冠醚基团。在这里，我们合成了一个新的三（冠醚）离子载体TriBCE，它由三个18冠-6基团连接到一个常见的邻苯乙烯-乙炔环三聚体中心组成，并利用TriBCE在纳米移液电极上辅助各种环境相关重金属离子（如Mg2+， Cu2+， Cd2+和Li+）和神经递质（多巴胺）的离子转移。三冠醚（TriBCE）的半波传递电位比单冠醚（DB18C6）低123 +/- 28 mV。测定了TriBCE与离子络合的结合常数、吉布斯自由能和化学计量系数，并与DB18C6进行了比较，结果表明，具有多个结合基团的离子载体使离子更容易转移。
Assisted ion transfer at a pipet-supported interface between two immiscible electrolyte solutions (ITIES) have become a prominent method for the detection of various ionic species and for studying ionic complexation. A typical ionophore contains one binding center to ions such as dibenzo-18-crown-6 (DB18C6). It is unknown how the detection of ions changes when assisted by an ionophore with multiple crown ether moieties. Here, we synthesized a new tris(crown ether) ionophore, TriBCE, which is composed of three 18-crown-6 moieties connected to a common o-phenylene ethynylene cyclic trimer center, and employed TriBCE for the assisted ion transfer of various environmentally relevant heavy-metal ions (i. e. Mg2+, Cu2+, Cd2+ and Li+) and a neurotransmitter (dopamine) at nanoITIES pipet electrodes. The half-wave transfer potentials for those ions were less positive by 123 +/- 28 mV when assisted by tris (crown ether), TriBCE, compared to mono(crown ether), DB18C6. The binding constants, Gibbs free energy, and the stoichiometric coefficients of ionic complexation with TriBCE were measured and compared to that of DB18C6 to reveal that ionophore with multiple binding moieties enables easier transfer of these ions.