Surface functionalization of quantum dots for biological applications
Surface functionalization of quantum dots for biological applications
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DOI：
10.1016/j.cis.2014.11.004
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发表时间：
2015-01-01
影响因子：
15.6
通讯作者：
Singh, Sanjay
中科院分区：
文献类型：
--
作者：
Karakoti, Ajay Singh;Shukla, Ritesh;Singh, Sanjay
量子点是一组表现出优异光学和电子特性的无机纳米材料，与传统荧光有机染料相比，在可调谐的宽激发光谱和窄发射光谱、信号亮度、高量子产率和光稳定性方面具有明显的优势。水溶性和表面功能化是生物研究中使用的量子点最常见的问题。这篇综述讨论了最近在提高水溶性、量子点表面生物分子功能化方面取得的研究进展，以及此类纳米颗粒生物功能化步骤中涉及的鲜为人知的化学。 (C) 2014 Elsevier B.V. 保留所有权利。
Quantum dots are a group of inorganic nanomaterials exhibiting exceptional optical and electronic properties which impart distinct advantages over traditional fluorescent organic dyes in terms of tunable broad excitation and narrow emission spectra, signal brightness, high quantum yield and photo-stability. Aqueous solubility and surface functionalization are the most common problems for QDs employed in biological research. This review addresses the recent research progress made to improve aqueous solubility, functionalization of biomolecules to QD surface and the poorly understood chemistry involved in the steps of bio-functionalization of such nanoparticles. (C) 2014 Elsevier B.V. All rights reserved.