Intraspecific genetic variation for anesthesia success in a New Zealand freshwater snail
Intraspecific genetic variation for anesthesia success in a New Zealand freshwater snail
复制标题
新西兰淡水蜗牛麻醉成功的种内遗传变异
DOI:
10.1007/s10709-020-00110-6
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发表时间:
2021
期刊:
影响因子:
1.5
通讯作者:
Neiman, Maurine
中科院分区:
文献类型:
--
作者:
Song, Qiudong;Magnuson, Richard;Jalinsky, Joseph;Roseman, Marissa;Neiman, Maurine
Intraspecific genetic variation can drive phenotypic variation even across very closely related individuals. Here, we demonstrate that genetic differences between snails are a major contributor to wide variation in menthol anesthesia success in an important freshwater snail model system,Potamopyrgus antipodarum. Anesthesia is used to immobilize organisms for experiments and surgical procedures and to humanely mitigate pain. This is the first example of which we are aware of a role for genetic variation in anesthesia success in a mollusk. These findings highlight the fact that using only one strain or lineage for many experiments will not provide a full picture of phenotypic variation, demonstrate the importance of optimizing biomedically relevant techniques and protocols across a variety of genetic backgrounds, illuminate a potential mechanism underlying previously documented challenges in molluscan anesthesia, and set the stage for powerful and humane manipulative experiments inP. antipodarum.
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DOI:
--
发表时间:
2007
期刊:
影响因子:
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