Prevalence of age-related maculopathy in the adult population in China: The Beijing eye study
Prevalence of age-related maculopathy in the adult population in China: The Beijing eye study
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DOI：
10.1016/j.ajo.2006.06.001
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发表时间：
2006-11-01
影响因子：
4.2
通讯作者：
Li, Jianjun
中科院分区：
文献类型：
--
作者：
Li, Yibin;Xu, Liang;Li, Jianjun
目的：评估中国大陆农村或城市地区成年中国人的年龄相关性黄斑病变（ARM）患病率。设计：基于人群的患病率研究。方法：该研究纳入了 5324 名受试者中的 4439 名受试者（年龄 40 岁或以上）（应答率 83.4%）。它在大北京的农村和城市地区举行。参与者接受了详细的眼科检查，包括眼底摄影。所有眼底照片均按照威斯康星州年龄相关黄斑病变分级系统进行分级。结果：4376 名 (98.6%) 受试者可获得眼底照片。 8655 名受试者中的 122 名 (1.4%) (95% CI 1.16% 至 1.66%) 眼睛或 4376 名受试者中的 63 名 (1.4%) (95% CI 1.09% 至 1.79%) 存在早期 ARM，8655 名受试者中有 12 名 (0-14%) 出现晚期 ARM (95% CI 0.06% 至 1.66%)。 0.22%）眼或 4376 名受试者中的 7 只（0.2%）（95% CI 0.04% 至 0.28%）受试者，以及 8655 名受试者中的 7 只（0.1%）眼（95% CI 0.02% 至 0.14%）或 4376 名受试者中的 6 只（0.1%）（95% CI 0.03% 至 0.28%）渗出性 ARM 作为晚期 ARM 的一部分（95% CI 0.03% 至 0.14%）。 0.25%）科目。早期ARM、晚期ARM和渗出性ARM的患病率分别从40～44岁组的0.61%、0.07%和0.07%增加到55～59岁组的1.66%、0.26%和0.26%，以及2.99%、0.90%和0.60%在75岁及以上的群体中。 ARM 是导致一名受试者 (0.023%) 视力障碍（较好眼的最佳矫正视力 < 20/60 且 >= 20/400）或失明（视力 < 20/400）的原因。 结论： ARM 导致的视力障碍在农村和城市地区的中国成年人口中相对较少见。
OBJECTIVE: To evaluate the prevalence of age-related maculopathy (ARM) in adult Chinese living in rural or urban regions of mainland China.DESIGN: Population-based prevalence study.METHODS: The study included 4439 subjects (aged 40 or more years) out of 5324 subjects invited to participate (response rate 83.4%). It was held in rural and urban regions of Greater Beijing. The participants underwent a detailed ophthalmic examination including fundus photography. All fundus photographs were graded by the Wisconsin Age,Related Maculopathy Grading System.RESULTS: Fundus photographs were available for 4376 (98.6%) subjects. Early ARM was present in 122 (1.4%) of 8655 (95% confidence interval [CI] 1.16% to 1.66%) eyes or 63 (1.4%) of 4376 (95% CI 1.09% to 1.79%) subjects, late ARM in 12 (0-14%) of 8655 (95% CI 0.06% to 0.22%) eyes or seven (0.2%) of 4376 (95% CI 0.04% to 0.28%) subjects, and exudative ARM as part of late ARM in seven (0.1%) of 8655 (95% CI 0.02% to 0.14%) eyes or six (0.1%) of 4376 (95% CI 0.03% to 0.25%) subjects. The prevalence of early ARM, late ARM, and exudative ARM, respectively, increased from 0.61%, 0.07%, and 0.07% in the 40-to-44-year age group, to 1.66%, 0.26%, and 0.26% in the 55,to 59-year group, and to 2.99%, 0.90%, and 0.60% in the group aged 75 years and older. ARM was causative for visual impairment (best-corrected visual acuity in the better eye, < 20/60 and >= 20/400) or blindness (visual acuity < 20/400) in one subject (0.023%).CONCLUSIONS: Visual impairment due to ARM was relatively uncommon in the adult Chinese population in rural and urban regions.