Correlation between anatomy and electrical activation in canine pulmonary veins
Correlation between anatomy and electrical activation in canine pulmonary veins
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DOI：
10.1161/01.cir.0000056765.97013.5e
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发表时间：
2003-03-25
期刊：
影响因子：
37.8
通讯作者：
Chen, PS
中科院分区：
文献类型：
--
作者：
Hamabe, A;Okuyama, Y;Chen, PS
背景-复杂的肌肉袖的几何形状和纤维方向在肺静脉（PVs）中的波前propagation.Methods和Results-We映射左上级PV（LSPV，n=7）和左下PV（LIPV，n=4）的狗与420双极电极（1毫米分辨率）的角色，并进行详细的组织学检查。在前LSPV-左心房（LA）交界处，心肌肌纤维定向垂直于PV血流。充满结缔组织的楔形导致PV和LA之间的肌肉完全分离或肌肉厚度突然增加（0.42 ± 0.12 vs 2.0 ± 0.31 mm，P
Background-The roles of complex muscle sleeve geometry and fiber orientation in the pulmonary veins (PVs) in wave-front propagation are poorly understood.Methods and Results-We mapped the left superior PV (LSPV, n=7) and left inferior PV (LIPV, n=4) of dogs with 420 bipolar electrodes (1-mm resolution) and performed detailed histological examination. In the anterior LSPV-left atrial (LA) junction, myocardial muscle fibers were oriented perpendicular to PV blood flow. A wedge filled with connective tissues led to a complete muscle separation or an abrupt increase in muscle thickness between the PV and LA (0.42+/-0.12 versus 2.0+/-0.31 mm, P