The Relation Between Event Related Potential and Working Memory in Healthy Subjects

The Relation Between Event Related Potential and Working Memory in Healthy Subjects
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健康受试者事件相关电位与工作记忆的关系

DOI:
10.3109/00207450009003267
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发表时间:
2000
影响因子:
2.2
通讯作者:
T. Ergenoglu
T. Ergenoglu
中科院分区:
医学4区
文献类型:
--
作者:
H. Beydağı;Ç. Özesmi;Alpaslan Yılmaz;Cem Süerd;T. Ergenoglu

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在许多研究中,事件相关电位的P300成分已被证明是记忆活动的有效指标。本研究探讨了短时记忆任务中事件相关电位各成分的波幅和潜伏期。对40名健康受试者进行了听觉诱发事件相关电位的研究。为评价受试者的短时记忆能力,用德尔菲语言为Windows编写了软件。软件的算法是呈现随机选择的四个不同数字4秒,将其移除并等待受试者的响应,如果响应为真,则增加一个数字,否则减少一个数字。经过20次试验,计算真实答案的平均回忆时间。回忆时长的被试P300潜伏期延长。P300潜伏期与回忆时间呈正相关。N1、P2、N2潜伏期和波幅与回忆时间无相关性。提示记忆问题与P300异常密切相关。
In numerous investigations the P300-component of the event related potential has proved a valid indicator of memory activities. The present study explores the amplitude and latency of the components of event-related potential regarding short-term memory task. Event related potentials, elicited by auditory stimuli, were recorded in 40 healthy subjects. For evaluating short term memory capacity of a subject, software in Delphi for Windows language was written. Algorithm of the software was the presentation of randomly selected four different digits for 4 seconds, removing it and waiting for subject's response, adding one digit, if response was true, otherwise decreased by one. After 20 trials, mean of recall time for true answers was computed. The subjects with high recall time showed prolonged latency of P300. A positive correlation was found between P300 latency and recall time. No correlation was found between N1, P2 and N2 latency or amplitude and recall time. These results suggest that memory problems are well correlated with the abnormalities of P300.
DOI: 10.1126/science.7434000
发表时间: 1980-01-01
期刊: SCIENCE
影响因子: 56.9
作者:
HALGREN, E;SQUIRES, NK;CRANDALL, PH
通讯作者: CRANDALL, PH
DOI: 10.1111/j.1469-8986.1983.tb00936.x
发表时间: 1983-01-01
期刊: PSYCHOPHYSIOLOGY
影响因子: 3.7
作者:
POLICH, J;HOWARD, L;STARR, A
通讯作者: STARR, A