Enhancing recruitment of African-American families into genetic research: lessons learned from Project SuGar.
Enhancing recruitment of African-American families into genetic research: lessons learned from Project SuGar.
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加强招募非裔美国家庭参与基因研究：SuGar 项目的经验教训。
DOI：
10.1007/s12687-010-0017-x
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发表时间：
2010
影响因子：
1.9
通讯作者：
Spruill,IdaJ
中科院分区：
文献类型：
--
作者：
Spruill,IdaJ
尽管少数民族在生物医学研究方面取得了一些成功，但非洲裔美国人家庭参与研究，特别是遗传研究的比例低于高加索人家庭（Bowen and Penchaszadeh Community Genet 11：189-190，2008）。非裔美国人的这种低参与率阻止了对疾病模式中特定种族差异的探索，并减少了对种族群体中特定疾病风险的识别（Bowen和Penchaszadeh Community Genet 11：189-190，2008）。虽然非洲裔美国人是异质性的，但很少有研究描述不同非洲裔美国人群体的有效招募策略，甚至更少的研究分享非洲裔美国人家庭参与遗传研究的有效策略。对SuGar项目（一项以社区为基础的遗传研究，重点关注受2型糖尿病影响的家庭）用于招募非裔美国人家庭参加遗传研究的招募策略进行了过程评估。我们的目标是招募400个受影响的非裔美国人家庭，我们的结果产生了672个家庭，（n= 672）。我们的成功可以归功于公民咨询委员会的成立、招聘方式、灵活的协议以及与社区卫生中心的正式协议。我们发现，非裔美国人家庭将参与研究，并提供切实的利益，以社会和利用耐心的感觉可以提高积极的招聘结果。本研究的数据可用于招募地理隔离的家庭进行遗传研究。
Despite some recruitment success in biomedical research among minorities, participation by African-American families into research, specifically genetic research, is lower than Caucasian families (Bowen and Penchaszadeh Community Genet 11:189–190, 2008). Such low participation rates by African-Americans prevent the exploration of specific ethnic differences in patterns of diseases and diminish the identification of specific disease risks among ethnic groups (Bowen and Penchaszadeh Community Genet 11:189–190, 2008). Although African-Americans are heterogeneous, few studies exist to describe effective recruitment strategies across diverse African-American populations, and even fewer studies share effective strategies for the enrollment of African-American families into genetic research. A process evaluation of recruitment strategies used by Project SuGar (a community-based genetic research study focusing on families affected by type 2 diabetes) to enroll African-American families into genetic research was conducted. Our goal was to enroll 400 affected African-American families, and our results yielded 672 families, (n= 672). Our success can be attributed to the formation of a Citizen Advisory Committee, recruitment style, flexible protocol, and formal agreement with community health centers. We found that African-American families will participate in research and that providing tangible benefits to the community and utilizing a sense of patience can enhance positive recruitment results. Data from this study may be used to recruit geographically isolated families into genetic research.