Vapor-Based Polymer Gradients
Vapor-Based Polymer Gradients
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DOI：
10.1002/marc.200800578
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发表时间：
2009-01-02
影响因子：
4.6
通讯作者：
Lahann, Joerg
中科院分区：
文献类型：
--
作者：
Elkasabi, Yaseen;Lahann, Joerg
采用化学气相沉积（CVD）共聚法制备了具有反应性表面组成梯度的聚合物涂层。将[2.2]对环芳烷的两种官能化衍生物以130 °角进料到双源CVD系统中，然后共聚并作为聚合物梯度沉积。红外和X射线光电子能谱（XPS）证实了本体聚合物内和表面的组成变化。通过操纵工艺参数，可以在宽范围的衬底上沉积定制的组成斜率的梯度。我们还能够选择性地将荧光标记的配体固定在反应性聚合物梯度上，使基于CVD的梯度表面成为制造生物分子基底的灵活平台。
Chemical vapor deposition (CVD) co-polymerization was used to fabricate polymer coatings, which comprise of reactive surface composition gradients. Two functionalized derivatives of [2.2]paracyclophane were fed into a two-source CVD system at a 130 0 angle, then copolymerized and deposited as a polymer gradient. Infrared and X-ray photoelectron spectroscopy (XPS) confirmed the compositional changes within the bulk polymer and at the surface. By manipulating process parameters, gradients of tailored compositional slope can be deposited on a wide range of substrates. We also were able to selectively immobilize fluorescence-labeled ligands onto the reactive polymer gradients, making CVD-based gradient surfaces a flexible platform for fabricating biomolecular substrates.