Depressed mood in individuals with schizophrenia: A comparison of retrospective and real-time measures.

Depressed mood in individuals with schizophrenia: A comparison of retrospective and real-time measures.
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精神分裂症患者的情绪低落:回顾性和实时措施的比较。

DOI:
10.1016/j.psychres.2015.03.008
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发表时间:
2015-06-30
影响因子:
11.3
通讯作者:
Kimhy, David
Kimhy, David
中科院分区:
医学2区
文献类型:
--
作者:
Blum, Lisa H.;Vakhrusheva, Julia;Saperstein, Alice;Khan, Samira;Chang, Rachel W.;Hansen, Marie C.;Zemon, Vance;Kimhy, David

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抑郁情绪在精神分裂症患者中普遍存在,导致功能障碍。通常,抑郁情绪是使用回顾性评估来评估的,在此期间,个体被要求回忆他们在过去一周或一个月的情绪。然而,由于精神分裂症患者可能表现出记忆困难,因此此类评估的结果可能存在偏差,可能导致不准确的临床特征和/或次优治疗。我们的目的是评估长期记忆对精神分裂症患者抑郁情绪的潜在影响。采用经验抽样方法(ESM),51名精神分裂症患者和22名健康对照者在两天内每天对他们的瞬间情绪进行10次评估,沿着对抑郁情绪、长期记忆、生活质量、社会功能和症状进行回顾性测量。即时抑郁情绪的ESM评估表现出区分效度和收敛效度。在精神分裂症组中,抑郁情绪的实时和回顾性测量之间存在显著相关性。然而,一旦控制了长期记忆引起的方差,实时和回顾性测量之间的关系就不再显著。研究结果表明,抑郁情绪的实时测量可能有助于克服精神分裂症患者中常见的长期记忆困难相关的一些限制。
Depressed mood is prevalent among individuals with schizophrenia, leading to difficulties in functioning. Typically, depressed mood is evaluated using retrospective assessments during which individuals are asked to recall their mood during the past week or month. However, as individuals with schizophrenia may display memory difficulties, the results of such assessments may be biased, potentially leading to inaccurate clinical characterizations and/or suboptimal treatment. Our aim was to assess the potential impact of long-term memory on depressed mood in individuals with schizophrenia. Employing an Experience Sampling Method (ESM) approach, 51 individuals with schizophrenia and 22 healthy controls rated their momentary emotions up to 10 times/day over a two-day period, along with retrospective measures of depressed mood, long-term memory, quality of life, social functioning, and symptoms. ESM assessment of real-time depressed mood demonstrated discriminant and convergent validity. Among the schizophrenia group, there was a significant correlation between the real-time and retrospective measures of depressed mood. However, once variance due to long-term memory was controlled, the relationship between the real-time and retrospective measure was no longer significant. The findings suggest that a real-time measure of depressed mood may allow overcoming some of the limitations associated with long-term memory difficulties common among individuals with schizophrenia.
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